After years of watching patients struggle with complicated routines and chase results through procedures, I knew there had to be a better way. That’s why I created the KaramMD Trifecta—a comprehensive, clinically backed skincare system that simplifies your routine without sacrificing results.
It’s as easy as washing your face, applying two pumps of serum, and finishing with three pumps of cream. In under five minutes, morning and night, you’re delivering 24-hour benefits to your skin—every single day. And because the system is easy to follow, you’re more likely to stick with it. The more consistent you are, the better your results become over time.
People often ask if Trifecta is worth the cost, especially when comparing it to standard over-the-counter products or the price tag of laser treatments. The truth is, if you’re going to do one thing for your skin, this is the smartest investment you can make.
The best part? Trifecta is clinically tested to deliver visible results in as little as 30 days, with transformative results in 90 days. Patients in their 30s, 40s, 50s, 60s, and 70s and beyond, have all report brighter, firmer, healthier-looking skin—with no downtime, no appointments, and no added steps.
This isn’t just a skincare system—it’s your daily, long-term strategy for younger-looking skin. And because it works every day, twice a day, the results keep building. That’s something no laser can match.
7 comments
Peggy B
I am thrilled that I found Dr. Karam"s youtube videos. I often get asked what I do to keep my skin looking so good and I always start by answering to wash their face at night and get the best skin care they can afford. Consistency is key! I agree. What is Dr. Karam’s opinion on red light therapy? I use it several times a week. I would love to know. The information on the different lasers was especially helpful and I have shared with many friends. Thank you for your time.
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KaramMD Skin replied:
Hi Peggy—Thanks for your comment! Red and near-infrared LED light therapy can be effective when used consistently, supporting collagen production and improving skin tone over time. It’s generally safe, especially when using FDA-cleared devices and following guidelines—though retinol can increase sensitivity. Quality varies widely, so look for devices with therapeutic wavelengths (630–850 nm), adequate power output, and safety certifications.
Chris
What do you think of the pixel 8 proced?
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KaramMD Skin replied:
Hi Chris—The Pixel 8 is an interesting new technology that’s gained attention in the aesthetic space, especially because it combines microneedling with radiofrequency (RF) energy. The idea is to stimulate collagen remodeling and tighten the skin—something we always aim to achieve in a minimally invasive way. That said, I always approach new treatments with a mix of optimism and caution. Options like RF microneedling can be helpful in addressing some signs of aging. Ultimately, the key is matching the right treatment to the right person. If you’re exploring Pixel 8, we would recommend seeing a qualified provider who can assess whether it aligns with your skin condition and goals. It’s not a one-size-fits-all solution—but it can be a tool in the toolbox in addition to a consistent, comprehensive skincare routine which is the foundation to youthful looking skin.
Julia Hayne
What is your opinion of nouvaderm laser? What is a safe level of depth to not harm fat /collagen reserve under skin in your opinion? Thx, Julia Hayne. I have been avoiding radio frequency microneedling for this reason. Is this any better?
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KaramMD Skin replied:
Hi Julia— Thank you for your comment! Dr. Karam often emphasizes the importance of customizing the depth of treatment to your individual skin type and concerns to achieve optimal results without compromising the underlying fat or collagen reserves. If you are considering laser treatments like NOUVADerm, it is essential to consult with a qualified professional who can assess your skin’s unique needs and determine the appropriate depth and modality to ensure safety and efficacy. As with any treatment of this kind, always proceed with caution and stay superficial.
Paula Bruno
Hi Dr Amir, Greetings from Melbourne, Australia. I watch your channel regularly and value all that you state. What is your opinion on collagen building injections and is it beneficial for the long term affect. Can you suggest any. My skincare routine is simple and applied daily as I work a 12 hour rotating roster. I recently started noticing fine lines around my mouth and drooping upper eyelids (looking very tied).
I am 65 years old, never needed or had anything done. What do you suggest. Would greatly appreciate your input. Many thanks in advance. Paula
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KaramMD Skin replied:
Hi Paula—Thanks for your comment! For Dr.Karam’s opinion on collagen-building injections, like Sculptra we suggest you watch this video he made on the topic: https://www.youtube.com/watch?v=oQ3d1Ru2DRs. In general, these treatments are not a replacement for a consistent, comprehensive skincare routine. We don’t typically recommend these kinds of injections for volume loss, but in some cases, a little can go a long way when used carefully to stimulate collagen without overfilling.
Cynthia Tillman
Does the trifecta have sunscreen.
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KaramMD Skin replied:
Hi Cynthia—Thanks for your comment! SPF will most likely never be added to the Trifecta for several reasons. Adding SPF to an anti-aging cream like Illuminate can affect the product’s texture, reduce the stability of the many active ingredients, and limit its use to daytime. Illuminate is meant to be used day and night so it wouldn’t really make sense to include sun protection. Sunscreen also requires frequent reapplication, which doesn’t align with how Illuminate is used only twice daily. By leaving SPF out, we can offer more flexibility, allowing our clients to pair the cream with a sunscreen that suits their specific needs while ensuring optimal performance of the active ingredients.
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