KaramMD Trifecta
The Complete Anti-Aging Routine
A simple skincare system proven to give you healthier, younger-looking skin in 3 easy steps—formulated with powerful active ingredients to target all aspects of aging skin simultaneously.
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PRODUCT OVERVIEW
If you want real results, skin that looks healthier and more youthful month after month, KaramMD Trifecta is for you. An innovative approach that consolidates up to 10 product categories into a 3 step routine, making it easy to remain committed and consistent with your skincare habits. Comprehensive skincare doesn’t need to be complicated and the Trifecta offers you a proven path on your journey to great skin.
Size:
- Rinse 2.5 fl oz 75 mL
- Quench 1 fl oz 30 mL.
- Illuminate 1.7 fl oz 50 mL
KEY INGREDIENTS
Aloe Vera: Soothes discomfort and hydrates skin.
Apple Amino Acids: Cleanse without stripping natural oils.
Arnica Extract: Calms irritation and reduces redness.
Broccoli Seed Oil: Supports skin barrier for moisture.
Willowherb Extract: Provides antioxidant protection.
Allantoin: Naturally exfoliates and reduces redness
Triple Vitamin C: Lightens dark spots & boosts natural glow.
Sodium Hyaluronate: Deeply hydrates and plumps skin.
Green Tea: Antioxidant protection and calms irritation.
Willowherb: Balances oil production and calms redness.
Licorice Root: Brightens skin and reduces discoloration.
Panthenol: Stimulates collagen production & skin repair.
Aloe: Hydrates, soothes, and helps reduce skin irritation.
Vitamin E: Strengthens defenses against premature aging.
Encapsulated Retinol: Works deeply to reduce fine lines and wrinkles.
Niacinamide: Balances skin tone and refines texture.
Peptide Complex: Supports the natural repair process.
Lipid Complex: Enhances elasticity and skin barrier.
Sodium Hyaluronate: Boosts hydration to reduce fine lines.
Botanical Lighteners: Naturally reduce pigmentation.
Edelweiss Flower Extract: Firms and protects skin.
Squalene: Strengthens the barrier and locks in moisture.
Hibiscus Flower: Supports body’s natural growth factors
Vitamin C & E: Antioxidants for skin protection and repair.
APPLICATION TIPS
- Use all 3 products in order: 01. Rinse--02. Quench--03. Illuminate.
- Trifecta needs to be used twice a day, every day.
- Use every morning and evening for 24 hours of continuous coverage.
- Consistency is key--do not skip applications.
- Apply on damp skin. No need to dry in between steps.
- Cover your entire face, including the under-eyes and eyelids.
- Don't forget the neck and décolleté.
- Use SPF every morning after your routine.
- Continue routine for at least 3-6 months for lasting changes.
HOW TO USE: TRIFECTA ROUTINE
Clinically Proven to Fight Aging Skin
The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:
100% of subjects had improvement in skin’s moisture.
100% of subjects had improvement in fine lines & wrinkles.
91% of subjects had improvement in skin’s firmness.
Clinically Proven to Fight Aging Skin
The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:
100% of subjects had improvement in skin’s moisture.
100% of subjects had improvement in fine lines & wrinkles.
91% of subjects had improvement in skin’s firmness.
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Truly Innovative
Anti-Aging Formulas
1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.
2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.
3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.
Truly Innovative
Anti-Aging Formulas
1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.
2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.
3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.
Great Skin Made Simple
The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta.
Great Skin Made Simple
The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta.
How to Use
Rinse: Apply to wet skin, massage in circular motions, then rinse clean.
Quench: Apply 2 pumps to slightly damp face, eye area, and neck.
Illuminate: Apply 3 pumps to face, eye area, and neck.
Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.
HOW TO USE: TRIFECTA ROUTINE
How to Use
Rinse: Apply to wet skin, massage in circular motions, then rinse clean.
Quench: Apply 2 pumps to slightly damp face, eye area, and neck.
Illuminate: Apply 3 pumps to face, eye area, and neck.
Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.
HOW TO USE: TRIFECTA ROUTINE
Skincare Advice You Can Trust
The Best Anti-Aging Ingredients
When assessing your skincare products, it is essential they include the following anti-aging ingredients. Each of these ingredients play a unique role in skin health and are crucial to achieving y...
Dr. Karam's Philosophy for an Effective Skincare Routine
I believe I’ve finally found the secret to anti-aging. After 20 years of experience—and a lot of patience (and patients) throughout my career—I came to understand that skincare is more than just t...
Trifecta 101: What You Need to Know When Starting Your New Skincare Routine
Whether you’re completely new to skincare or transitioning to the Trifecta system, this guide will walk you through what to expect as you begin your skincare journey.
INGREDIENTS
RINSE
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
QUENCH
Aqua/Water/Eau, Pentylene Glycol, Magnesium Ascorbyl Phosphate, Aminopropyl Ascorbyl Phosphate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Ziziphus Spina-Christi (Christ’s Thorn) Leaf Extract, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Camellia Sinensis (Tea Camellia) Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Trehalose, Panthenol, Aloe Barbadensis (Aloe Vera) Leaf Juice, Tocopherol, Glycerin, Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Sodium Nitrate, Disodium Phosphate, Polysorbate 60, Citric Acid, Sodium Phosphate, Potassium Sorbate, PPG-26-Buteth-26, Sodium Benzoate, PEG-40 Hydrogenated Castor Oil, Glyoxal, Sodium Metabisulfite, Sodium Hydroxide.
ILLUMINATE
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Caprylic/Capric Triglyceride, Glycerin, Jojoba Oil/Macadamia Seed Oil Esters, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, Coco-Caprylate/Caprate, Dimethicone, Niacinamide, Cetearyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Glucoside, Brassica Oleracea Italica (Broccoli) Seed Oil, Retinol, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Phytosterols, 3-O-Ethyl Ascorbic Acid, Potassium Azeloyl Diglycinate, Leontopodium Alpinum Callus Culture Extract, Squalane, Phytosteryl Macadamiate, Hibiscus Abelmoschus (Musk Okra) Extract, Bellis Perennis (Daisy) Flower Extract, Calendula Officinalis (Marigold) Flower Extract*, Hexylresorcinol, Arnica Montana (Mountain Arnica) Flower Extract, Melissa Officinalis (Lemon Balm) Leaf Extract, Oryza Sativa (Rice) Extract, Leuconostoc Ferment Filtrate, Superoxide Dismutase, Soybean Peroxidase, Tocopherol, Cetyl alcohol, Phenoxyethanol, Biosaccharide Gum-1, Glyceryl Stearate, PEG-100 Stearate, Ceteareth-20, Butylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Polysorbate 60, Sorbitan Isostearate, Xanthan Gum, PEG-20, Sucrose Palmitate, Sucrose Tristearate, Tocopheryl Acetate, Glyceryl Linoleate, Alcohol Denat., Phenethyl Alcohol, Disodium Phosphate, Citric Acid, Potassium Sorbate, Sodium Hydroxide, Iodopropynyl Butylcarbamate, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
Aqua/Water/Eau, Pentylene Glycol, Magnesium Ascorbyl Phosphate, Aminopropyl Ascorbyl Phosphate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Ziziphus Spina-Christi (Christ’s Thorn) Leaf Extract, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Camellia Sinensis (Tea Camellia) Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Trehalose, Panthenol, Aloe Barbadensis (Aloe Vera) Leaf Juice, Tocopherol, Glycerin, Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Sodium Nitrate, Disodium Phosphate, Polysorbate 60, Citric Acid, Sodium Phosphate, Potassium Sorbate, PPG-26-Buteth-26, Sodium Benzoate, PEG-40 Hydrogenated Castor Oil, Glyoxal, Sodium Metabisulfite, Sodium Hydroxide.
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Caprylic/Capric Triglyceride, Glycerin, Jojoba Oil/Macadamia Seed Oil Esters, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, Coco-Caprylate/Caprate, Dimethicone, Niacinamide, Cetearyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Glucoside, Brassica Oleracea Italica (Broccoli) Seed Oil, Retinol, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Phytosterols, 3-O-Ethyl Ascorbic Acid, Potassium Azeloyl Diglycinate, Leontopodium Alpinum Callus Culture Extract, Squalane, Phytosteryl Macadamiate, Hibiscus Abelmoschus (Musk Okra) Extract, Bellis Perennis (Daisy) Flower Extract, Calendula Officinalis (Marigold) Flower Extract*, Hexylresorcinol, Arnica Montana (Mountain Arnica) Flower Extract, Melissa Officinalis (Lemon Balm) Leaf Extract, Oryza Sativa (Rice) Extract, Leuconostoc Ferment Filtrate, Superoxide Dismutase, Soybean Peroxidase, Tocopherol, Cetyl alcohol, Phenoxyethanol, Biosaccharide Gum-1, Glyceryl Stearate, PEG-100 Stearate, Ceteareth-20, Butylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Polysorbate 60, Sorbitan Isostearate, Xanthan Gum, PEG-20, Sucrose Palmitate, Sucrose Tristearate, Tocopheryl Acetate, Glyceryl Linoleate, Alcohol Denat., Phenethyl Alcohol, Disodium Phosphate, Citric Acid, Potassium Sorbate, Sodium Hydroxide, Iodopropynyl Butylcarbamate, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
Frequently Asked Questions
Our caring team of experts has the answers.
How frequently should I be using the Trifecta?
All products should be used twice a day, every day. Adherence to the recommended dosage of twice a day, every day, is paramount. The efficacy of the Trifecta regimen is well-documented in our clinicals, but success hinges on your unwavering dedication. Skipping even a few days can compromise the synergistic effects of the Trifecta regimen, necessitating a reset and extending the timeline to witness desired results.
Do I need different products morning & night?
We believe that cleansing & moisturizing properly are all that is needed to protect your skin from external stressors. The ingredient deck in all three products has been strategically designed to benefit you both am & pm with no need to switch, add or omit products.
How long does the Trifecta last?
The Trifecta should last you around 30 days across all products if using them twice a day as recommended.
Do I need sunscreen with the Trifecta?
Yes! Sunscreen should be part of any daily routine.
When will I see results with the Trifecta?
It takes 28-days for skin cells to turn over, which means in order to see a difference in your skin from KaramMD products, you need to use them consistently for at least a month. That being said, significant improvements, encompassing texture, tone, and overall radiance, manifest with consistent application over an extended period, typically spanning 3 to 6 months. Adherence to the recommended dosage of twice a day, every day, is paramount.
This product is rated 4.7 of 5.0 stars.
It has received 1289 reviews.
- SSScotland S.Verified Buyer34 minutes agoRated 5 out of 5 stars“No Filters Needed — My Skin’s Never Looked Better
I rarely write reviews, but the Karam MD Trifecta Facial Care System deserves all the praise. I’ve been using it consistently for months now, and the transformation in my skin is undeniable.
My complexion looks brighter, more even, and — no exaggeration — healthier overall. There's this bounce and firmness to my skin that I haven’t felt in years. Friends and family have commented on how “refreshed” or “well-rested” I look, which I take as the ultimate compliment because trust me, I’m not getting more sleep!
What I love most is how this system takes the guesswork out of skincare. Each product works seamlessly together, and it doesn’t feel overwhelming or like a chore to stick with it. The texture of the formulas is luxurious, and I actually look forward to using them. As someone who’s tried countless routines over the years, I can confidently say this one delivers. It’s elegant, effective, and worth every bit of hype.
P.S. Dr. Karam — if you ever see this, we would love a travel-size version of the Trifecta system! I know the current sizes are technically travel-appropriate, but when space really counts, some littles for grab-and-go would be a total dream.
KSKaramMD Skin12 seconds agoThank you for your wonderful review, Scotland! We're absolutely thrilled to hear about your transformative journey with the Trifecta. It's particularly touching to hear about the remarkable improvements you've experienced—from the enhanced brightness and evenness to that youthful bounce and firmness you're seeing in your skin. These are exactly the kind of results we aim for with our formulations! We love that others are noticing your radiant transformation too, with those wonderful comments about looking refreshed and well-rested. Your appreciation of our system's seamless integration and user-friendly approach truly validates our commitment to creating effective, uncomplicated skincare solutions. And thank you for that thoughtful suggestion about travel sizes—we love hearing ideas from our dedicated customers! Your enthusiasm and trust in our products mean the world to us, and we're deeply grateful to have you as part of the KaramMD Skin community. Thank you for taking the time to share your inspiring experience with us!
- EFEva Fountain M.Verified Buyer3 hours agoRated 5 out of 5 starsTrifecta really works
I am 75 years old & have always tried to use the best skincare products & also RetinA. Trifecta really works. I have only been using it since February 2025. I love the way my skin is changing for the good. Pores are shrinking, dark spots are lightening at this point, skin is brighter & feels smooth. I’m very pleased with trifecta. It is costly but considering you only use the trio once or twice a day & it is so easy to use. I’m so glad I saw Dr Karan’s skincare video on YouTube. I get compliments all the time saying I look years younger! Makes my day!
KSKaramMD Skin3 hours agoThank you for your wonderful review, Eva ! We're absolutely thrilled to hear about your amazing journey with Trifecta and how it's transforming your skin. It's particularly touching to hear about the significant improvements you've experienced—from shrinking pores and lightening dark spots to brighter, smoother skin—these are exactly the kind of transformative results we aim for with our formulations. We love that you've noticed such positive changes and are receiving compliments about looking years younger! Your perspective on the value of the system, especially as someone with extensive experience using high-quality skincare products, truly validates our commitment to creating exceptional skincare solutions. We're deeply moved by your trust in our products and Dr. Karam's expertise, and we're honored to have you as part of the KaramMD Skin community. Thank you for sharing your inspiring experience with us!
- KBKaren B.Verified Buyer3 hours agoRated 5 out of 5 starsSoft, Glowing, Healthy skin!
So far so good! I just started month 3, and am impressed with how healthy and glowing my skin looks and feels. I have very large pores, and have enjoyed less congestion, and diminished pore size. I look forward to seeing the impact on fine lines and wrinkles! This system is so quick and easy to use - it is easy to stay consistent. I haven't missed one application!
KSKaramMD Skin3 hours agoThank you for your wonderful review, Karen ! We're absolutely thrilled to hear about your amazing three-month journey with Trifecta. It's particularly touching to hear about the significant improvements you've experienced with your pore size and skin congestion—these are exactly the kind of transformative results we aim for with our formulations. We love that you've noticed such positive changes in your skin's health and glow! Your dedication to consistency with the system is truly inspiring, and we're just as excited as you are to see your continued results with fine lines and wrinkles. Your appreciation of our streamlined, easy-to-use system truly validates our commitment to creating effective, uncomplicated skincare solutions. Your trust in our products means the world to us, and we're deeply grateful to have you as part of the KaramMD Skin community. Thank you for sharing your inspiring experience with us!
- CSChristina S.Verified Buyer19 hours agoRated 5 out of 5 starsGame changer
I’ve used another high-end line for years & was happy with it. However, I was intrigued so tried Trifecta. Wow. I had no idea in a short amount of time, my skin could look even better than before! At 51, I’m a customer for life!!
KSKaramMD Skin3 hours agoThank you for your wonderful review, Christina ! We're absolutely thrilled to hear about your remarkable experience with Trifecta. It's particularly touching to hear how, even after being satisfied with another high-end skincare line, you've discovered even better results with our products—these are exactly the kind of transformative outcomes we aim for with our formulations. We love that at 51, you're experiencing such noticeable improvements in your skin in such a short time. Your commitment to making Trifecta a lifelong part of your skincare journey truly validates our dedication to creating exceptional skincare solutions. We're deeply grateful to have you as part of the KaramMD Skin community. Thank you for sharing your inspiring experience with us!