KaramMD Trifecta
The Complete Anti-Aging Routine
The KaramMD Trifecta is a simple skincare system proven to give you healthier, younger-looking skin in 3 easy steps—formulated to target all aspects of aging skin simultaneously.
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PRODUCT OVERVIEW
The KaramMD Trifecta is an innovative, clinically proven skincare approach. It consolidates up to 10 product categories into a 3 step routine, making it easy to stay consistent and see results.
Make sure to make sure to use Trifecta consistently twice a day for at least a month to see results. This is critical because it takes 28-days for skin cells to turn over. Significant improvements in texture, tone, and radiance show after 3-6 months.
Skincare doesn’t need to be complicated and the Trifecta offers you a proven path on your journey to great skin.
Size:
- Rinse 2.5 fl oz 75 mL
- Quench 1 fl oz 30 mL.
- Illuminate 1.7 fl oz 50 mL
KEY INGREDIENTS
Aloe Vera: Soothes discomfort and hydrates skin.
Apple Amino Acids: Cleanse without stripping natural oils.
Arnica Extract: Calms irritation and reduces redness.
Broccoli Seed Oil: Supports skin barrier for moisture.
Willowherb Extract: Provides antioxidant protection.
Allantoin: Naturally exfoliates and reduces redness
Triple Vitamin C: Lightens dark spots & boosts natural glow.
Sodium Hyaluronate: Deeply hydrates and plumps skin.
Green Tea: Antioxidant protection and calms irritation.
Willowherb: Balances oil production and calms redness.
Licorice Root: Brightens skin and reduces discoloration.
Panthenol: Stimulates collagen production & skin repair.
Aloe: Hydrates, soothes, and helps reduce skin irritation.
Vitamin E: Strengthens defenses against premature aging.
Encapsulated Retinol: Works deeply to reduce fine lines and wrinkles.
Niacinamide: Balances skin tone and refines texture.
Peptide Complex: Supports the natural repair process.
Lipid Complex: Enhances elasticity and skin barrier.
Sodium Hyaluronate: Boosts hydration to reduce fine lines.
Botanical Lighteners: Naturally reduce pigmentation.
Edelweiss Flower Extract: Firms and protects skin.
Squalene: Strengthens the barrier and locks in moisture.
Hibiscus Flower: Supports body’s natural growth factors
Vitamin C & E: Antioxidants for skin protection and repair.
How to Use
Rinse: Apply to wet skin, massage in circular motions, then rinse clean.
Quench: Apply 2 pumps to slightly damp face, eye area, and neck.
Illuminate: Apply 3 pumps to face, eye area, and neck.
Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.
HOW TO USE: TRIFECTA ROUTINE
How to Use
Rinse: Apply to wet skin, massage in circular motions, then rinse clean.
Quench: Apply 2 pumps to slightly damp face, eye area, and neck.
Illuminate: Apply 3 pumps to face, eye area, and neck.
Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.
HOW TO USE: TRIFECTA ROUTINE
Clinically Proven to Fight Aging Skin
The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:
100% of subjects had improvement in skin’s moisture.
100% of subjects had improvement in fine lines & wrinkles.
91% of subjects had improvement in skin’s firmness.
Clinically Proven to Fight Aging Skin
The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:
100% of subjects had improvement in skin’s moisture.
100% of subjects had improvement in fine lines & wrinkles.
91% of subjects had improvement in skin’s firmness.
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Truly Innovative
Anti-Aging Formulas
1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.
2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.
3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.
Truly Innovative
Anti-Aging Formulas
1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.
2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.
3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.
Great Skin Made Simple
The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta.
Great Skin Made Simple
The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta.
Skincare Advice You Can Trust
The Best Anti-Aging Ingredients
When assessing your skincare products, it is essential they include the following anti-aging ingredients. Each of these ingredients play a unique role in skin health and are crucial to achieving y...
Dr. Karam's Philosophy for an Effective Skincare Routine
I believe I’ve finally found the secret to anti-aging. After 20 years of experience—and a lot of patience (and patients) throughout my career—I came to understand that skincare is more than just t...
Trifecta 101: What You Need to Know When Starting Your New Skincare Routine
Whether you’re completely new to skincare or transitioning to the Trifecta system, this guide will walk you through what to expect as you begin your skincare journey.
INGREDIENTS
RINSE
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
QUENCH
Aqua/Water/Eau, Pentylene Glycol, Magnesium Ascorbyl Phosphate, Aminopropyl Ascorbyl Phosphate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Ziziphus Spina-Christi (Christ’s Thorn) Leaf Extract, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Camellia Sinensis (Tea Camellia) Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Trehalose, Panthenol, Aloe Barbadensis (Aloe Vera) Leaf Juice, Tocopherol, Glycerin, Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Sodium Nitrate, Disodium Phosphate, Polysorbate 60, Citric Acid, Sodium Phosphate, Potassium Sorbate, PPG-26-Buteth-26, Sodium Benzoate, PEG-40 Hydrogenated Castor Oil, Glyoxal, Sodium Metabisulfite, Sodium Hydroxide.
ILLUMINATE
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Caprylic/Capric Triglyceride, Glycerin, Jojoba Oil/Macadamia Seed Oil Esters, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, Coco-Caprylate/Caprate, Dimethicone, Niacinamide, Cetearyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Glucoside, Brassica Oleracea Italica (Broccoli) Seed Oil, Retinol, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Phytosterols, 3-O-Ethyl Ascorbic Acid, Potassium Azeloyl Diglycinate, Leontopodium Alpinum Callus Culture Extract, Squalane, Phytosteryl Macadamiate, Hibiscus Abelmoschus (Musk Okra) Extract, Bellis Perennis (Daisy) Flower Extract, Calendula Officinalis (Marigold) Flower Extract*, Hexylresorcinol, Arnica Montana (Mountain Arnica) Flower Extract, Melissa Officinalis (Lemon Balm) Leaf Extract, Oryza Sativa (Rice) Extract, Leuconostoc Ferment Filtrate, Superoxide Dismutase, Soybean Peroxidase, Tocopherol, Cetyl alcohol, Phenoxyethanol, Biosaccharide Gum-1, Glyceryl Stearate, PEG-100 Stearate, Ceteareth-20, Butylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Polysorbate 60, Sorbitan Isostearate, Xanthan Gum, PEG-20, Sucrose Palmitate, Sucrose Tristearate, Tocopheryl Acetate, Glyceryl Linoleate, Alcohol Denat., Phenethyl Alcohol, Disodium Phosphate, Citric Acid, Potassium Sorbate, Sodium Hydroxide, Iodopropynyl Butylcarbamate, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
Aqua/Water/Eau, Pentylene Glycol, Magnesium Ascorbyl Phosphate, Aminopropyl Ascorbyl Phosphate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Ziziphus Spina-Christi (Christ’s Thorn) Leaf Extract, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Camellia Sinensis (Tea Camellia) Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Trehalose, Panthenol, Aloe Barbadensis (Aloe Vera) Leaf Juice, Tocopherol, Glycerin, Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Sodium Nitrate, Disodium Phosphate, Polysorbate 60, Citric Acid, Sodium Phosphate, Potassium Sorbate, PPG-26-Buteth-26, Sodium Benzoate, PEG-40 Hydrogenated Castor Oil, Glyoxal, Sodium Metabisulfite, Sodium Hydroxide.
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Caprylic/Capric Triglyceride, Glycerin, Jojoba Oil/Macadamia Seed Oil Esters, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, Coco-Caprylate/Caprate, Dimethicone, Niacinamide, Cetearyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Glucoside, Brassica Oleracea Italica (Broccoli) Seed Oil, Retinol, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Phytosterols, 3-O-Ethyl Ascorbic Acid, Potassium Azeloyl Diglycinate, Leontopodium Alpinum Callus Culture Extract, Squalane, Phytosteryl Macadamiate, Hibiscus Abelmoschus (Musk Okra) Extract, Bellis Perennis (Daisy) Flower Extract, Calendula Officinalis (Marigold) Flower Extract*, Hexylresorcinol, Arnica Montana (Mountain Arnica) Flower Extract, Melissa Officinalis (Lemon Balm) Leaf Extract, Oryza Sativa (Rice) Extract, Leuconostoc Ferment Filtrate, Superoxide Dismutase, Soybean Peroxidase, Tocopherol, Cetyl alcohol, Phenoxyethanol, Biosaccharide Gum-1, Glyceryl Stearate, PEG-100 Stearate, Ceteareth-20, Butylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Polysorbate 60, Sorbitan Isostearate, Xanthan Gum, PEG-20, Sucrose Palmitate, Sucrose Tristearate, Tocopheryl Acetate, Glyceryl Linoleate, Alcohol Denat., Phenethyl Alcohol, Disodium Phosphate, Citric Acid, Potassium Sorbate, Sodium Hydroxide, Iodopropynyl Butylcarbamate, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
Frequently Asked Questions
Our caring team of experts has the answers.
How frequently should I be using the Trifecta?
All products should be used twice a day, every day. Adherence to the recommended dosage of twice a day, every day, is paramount. The efficacy of the Trifecta regimen is well-documented in our clinicals, but success hinges on your unwavering dedication. Skipping even a few days can compromise the synergistic effects of the Trifecta regimen, necessitating a reset and extending the timeline to witness desired results.
Do I need different products morning & night?
We believe that cleansing & moisturizing properly are all that is needed to protect your skin from external stressors. The ingredient deck in all three products has been strategically designed to benefit you both am & pm with no need to switch, add or omit products.
How long does the Trifecta last?
The Trifecta should last you around 30 days across all products if using them twice a day as recommended.
Do I need sunscreen with the Trifecta?
Yes! Sunscreen should be part of any daily routine.
When will I see results with the Trifecta?
It takes 28-days for skin cells to turn over, which means in order to see a difference in your skin from KaramMD products, you need to use them consistently for at least a month. That being said, significant improvements, encompassing texture, tone, and overall radiance, manifest with consistent application over an extended period, typically spanning 3 to 6 months. Adherence to the recommended dosage of twice a day, every day, is paramount.
This product is rated 4.7 of 5.0 stars.
It has received 1602 reviews.
- MCMaria C.Verified BuyerWhat are your skin concerns? Uneven Skin Tone / Discoloration , Fine Lines & Wrinkles, General Aging, Loss of Elasticity , Skin Texture10 hours agoWhat are your skin concerns? Uneven Skin Tone / Discoloration , Fine Lines & Wrinkles, General Aging, Loss of Elasticity , Skin TextureRated 5 out of 5 starsAmazing results after 3 years!
I’m 55 years old and have been using the KaramMD Trifecta for three years. Just as Dr. Karam recommends, I only use these three products, and the results have been spectacular. My friends often tell me I look like I’m 30! The creams have kept my skin youthful, controlled my sun spots, and helped minimize wrinkles without the need for Botox, fillers, or any other treatments. I truly feel these products have kept my skin healthy, glowing, and naturally youthful.
KSKaramMD Skin1 hour agoThank you so much for your heartfelt message, Maria! We’re truly honored to have been part of your skincare journey for the past three years! The fact that others are noticing your glow and youthful appearance is the best kind of feedback, and a testament to your consistency and care. Thank you again for your trust and for being such a valued part of the KaramMD community!
- JFJanet F.Verified ReviewerWhat are your skin concerns? General Aging21 hours agoWhat are your skin concerns? General AgingRated 5 out of 5 starsVertical Restore
Sitting in the airport lounge as I return home from my vertical restore with Dr Karam, I’m really amazed at how smooth everything went with my procedure. I’m 7 days out and I feel fabulous and can’t believe the level of care and attention I received from the entire Karam team. True professionals with the magic of combining professionalism with compassion and care. My surgery went well and I was never in any pain. That really surprised me. First three days I had some discomfort but no pain. Dr Karam is truly special. My experience completely exceeded my expectations. Delightful.
- JHJake H.Verified BuyerWhat are your skin concerns? General Aging, Fine Lines & Wrinkles, Uneven Skin Tone / Discoloration , Environmental Damage, DrynessYesterdayWhat are your skin concerns? General Aging, Fine Lines & Wrinkles, Uneven Skin Tone / Discoloration , Environmental Damage, DrynessRated 5 out of 5 starsThree Years of Transformative Results
I’ve been using Trifecta Skincare for over three years, and it has completely transformed my skin. My complexion is clearer, smoother, and healthier-looking than ever. The products are powerful yet gentle, and I love that I can trust them to deliver consistent results without irritation. I get compliments all the time on my skin, and I truly credit Trifecta for helping me feel confident in my natural look. After years of trying different products, I finally found a routine I’ll never give up.
KSKaramMD Skin3 minutes agoThank you so much for your thoughtful review, Jake! We’re incredibly grateful to have been part of your routine for the past three years! The fact that you’ve found a routine you truly trust, and one that consistently delivers, is exactly what we hope every customer experiences. Thank you again for your continued support and for being such a valued part of the KaramMD community!
- SLShannon L.Verified BuyerWhat are your skin concerns? Fine Lines & Wrinkles, General Aging, Uneven Skin Tone / Discoloration , Oiliness, SensitivityYesterdayWhat are your skin concerns? Fine Lines & Wrinkles, General Aging, Uneven Skin Tone / Discoloration , Oiliness, SensitivityRated 5 out of 5 starsLife-Changing Results – My Skin Has Never Looked Better!
I've tried countless skincare lines over the years, but nothing – and I mean nothing – has transformed my skin the way the Trifecta system from KaramMD has.
Within just a few weeks of consistent use, I started to notice a remarkable difference in the texture of my skin. It became visibly smoother, softer, and more radiant – almost like I was gently shedding years of dullness. I used to struggle with uneven skin and rough patches, but now my face feels like silk.
What really blew me away, though, was how dramatically my fine lines have diminished. Especially around my eyes and mouth, where I was beginning to see deeper creases. The improvement is not subtle – my skin looks noticeably firmer, more youthful, and overall healthier. Friends and family have been asking what I’m doing differently, and I’m proudly telling them: KaramMD Trifecta.
I also appreciate how simple and effective the system is. No cluttered counter, no 10-step routine – just a few high-performance products that work beautifully together. I have used other very well known expensive clinical products for many years and this system has done more to improve my skin in just a few weeks with visible results!
If you’re on the fence or tired of trying products that overpromise and underdeliver, give the Trifecta a shot. It's one of the best investments I’ve made in my skin – and honestly, in my confidence.