01.
Retinol - 10/10
If I could recommend only one anti-aging skincare ingredient, it would probably be retinol.
Very few ingredients have the level of scientific evidence behind them that retinol does. It stimulates collagen, improves skin texture, softens fine lines, helps with pigmentation, and even improves acne.
It’s one of the true foundational ingredients in skincare.
The biggest issue is irritation. A lot of people try retinol, overdo it, get inflamed, and quit too early. That’s actually one of the reasons I developed the KaramMD Trifecta system. I wanted patients to be able to use powerful active ingredients consistently without constantly battling irritation and barrier damage.
Because consistency matters more than intensity.
























15 comments
Victoria Truchan
Do you do eye surgery (lower eye) for out of state patients?
If so, how do I get the necessary information?
Thanks
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KaramMD Skin replied:
Hi Victoria — Thank you for your comment! Yes, Dr. Karam does see out-of-state patients. The best next step is to submit a consultation request through his website, where you can share your photos and goals and his surgical team will guide you through the process from there: https://www.drkaram.com/getting-started/
masha bardacos
Thank you for the learning curve. You are always on point. You have a library in your brain all things related to face and skin. Listen Dr. Karem please address the LYMA LASER It is not instead of a face lift at all. It is to maintain and keep your skin Tight and toned. It is for home use and is expensive but if it delivers then it would be worth it. Yes of course our Martha Stewart at 85 is really into it. Also several girlfriends as well when going somewhere special. They use Preparation H . Under their eyes. You know the Hemroid cream. You wash it off before going to bed. Gives a nice overall effect.
Heather Mouzourakis
I’ve been using your trifecta for over a year now and LOVE IT! My only complaint would be packaging waste. The bottles a beautiful and refills could easily be sold so we weren’t throwing away the outer bottles every month. Just extremely wasteful.
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KaramMD Skin replied:
Hi Heather—Thank you for your comment and for your loyalty over the past year — it truly means everything to us! Your feedback on packaging is something we hear and take seriously. The airless, opaque design is essential to protecting the integrity of our clinically tested active ingredients , particularly Retinol and Vitamin C, which degrade quickly when exposed to light and air , but we completely understand that sustainability matters, and a refillable system is absolutely something we’re exploring for the future. Thank you for caring about both your skin and the planet , feedback like yours is exactly what shapes where we go next.
Tori
Would you provide the info where Neda bought her sunscreen visor/face/neck covering, please? I have a similar hat, but covering my hair has always contained too much heat for me; I prefer visors anytime I’m outdoors.
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KaramMD Skin replied:
Hi Tori—Thank you for your comment! Neda’s sun shield is from Coolibar.
Donalda
Thank you so much for your information on skin treatments and care. What retinol product would you recommend for an aging face.
Thank you.
Donalda
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KaramMD Skin replied:
Hi Donalda — Thank you for your comment! Dr. Karam developed Illuminate specifically to address this. It delivers Retinol via a patented encapsulated complex alongside over a dozen other clinically tested active ingredients including Niacinamide, Vitamin C, peptides, and powerful botanical brighteners, all working together to support collagen production, improve skin texture, and reduce the appearance of fine lines and wrinkles. Unlike traditional standalone Retinol products, Illuminate is formulated to be well tolerated by all skin types, including sensitive skin, while still delivering meaningful, measurable results.
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