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4.7
Rated 4.7 out of 5 stars
1,246 Reviews

A simple skincare system proven to give you healthier, younger-looking skin in 3 easy steps—formulated with powerful active ingredients to target all aspects of aging skin simultaneously.

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MD Formulated

Clinically Proven

Premium Ingredients

For All Skin Types

Cruelty Free

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

Read the KaramMD Journal

Skincare Advice You Can Trust

The Best Anti-Aging Ingredients

The Best Anti-Aging Ingredients

When assessing your skincare products, it is essential they include the following anti-aging ingredients. Each of these ingredients play a unique role in skin health and are crucial to achieving y...

Dr. Karam's Philosophy for an Effective Skincare Routine

Dr. Karam's Philosophy for an Effective Skincare Routine

I believe I’ve finally found the secret to anti-aging. After 20 years of experience—and a lot of patience (and patients) throughout my career—I came to understand that skincare is more than just t...

KaramMD Trifecta skincare routine: Rinse Daily Cleanser, Quench Vitamin C Serum, and Illuminate Anti-Aging Cream held in a single hand.

Trifecta 101: What You Need to Know When Starting Your New Skincare Routine

Whether you’re completely new to skincare or transitioning to the Trifecta system, this guide will walk you through what to expect as you begin your skincare journey.

INGREDIENTS

Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.

*Organic Ingredient

Frequently Asked Questions

Our caring team of experts has the answers.

4.7
Rated 4.7 out of 5 stars
Based on 1,246 reviews
1,246 reviews
  • KP
    Kim P.
    Verified Buyer
    17 seconds ago
    Rated 5 out of 5 stars
    Amazing Results!

    I no longer do Botox because of the amazing results I have from using the KaramMD Trifecta along with Enrich & Polish! Thank you Dr. Karam!

  • SH
    Suzanne H.
    Verified Buyer
    4 hours ago
    Rated 5 out of 5 stars
    IT REALLY WORKS!

    Wow this product really works! After years of trying different skin care regimens this showed the best results. My skin is brighter and has a natural shine again!

  • DS
    Deniece S.
    Verified Reviewer
    14 hours ago
    Rated 5 out of 5 stars
    Simple and Effective

    Constantly on the go for work, the years of carrying multiple travel size bottles of skin care days were over when I found out about Karam MD Trifecta on youtube 2 years ago. Not long after, I travelled to the US and starting to experience the Trifecta and was amazed by how affective 2 btls of skincare could work so well. Consistency is the key as always advised by Dr Karam. Within a few shore weeks, skin glows and taut . Smoothness and moisture level on the forehead was specifically obvious for me. I'm glad that the Trifecta is shipped internationally now that I can order from Australia, Singapore, Germany. Thanks for making it simple and effective ! Trifecta is my trusted travel companion. Appreciate Dr Karam for the helpful tips on skin health on youtube. Thank you !

  • DD
    Debbie D.
    Verified Buyer
    23 hours ago
    Rated 5 out of 5 stars
    My Skin Care

    I love using Trifecta my skin and my skin looks great everyday and it’s so quick and easy to use. I had so many steps in my routine before . Now I just use the Trifecta every day and night and I don’t worry if I have all that I need I know I have everything I need. I also do use ensure in the evening and I love it also! My skin would be dry and irritated on and off not now not one time since using trifecta.