Trifecta combines all the most powerful, science-backed anti-aging ingredients, including Retinol, Vitamin C, Niacinamide, Peptides, and Hyaluronic Acid, and 20+ other active ingredients into a single easy-to-use system.
In three quick steps, that take less than five minutes a day, you’re giving your skin everything it needs to resist and reverse fine lines, wrinkles, dullness, and loss of elasticity.
But, visible, lasting results don’t happen with skincare alone. The right routine also requires the Three Cs: commitment, consistency, and continuity.
You must commit to using the routine every day, apply it consistently twice a day, and continue month after month. The payoff? Smoother, firmer, brighter skin that continues to improve over time.
I speak all the time about the journey your skin will take when you commit to a comprehensive routine, so let’s go through that skincare journey, and discuss how your skin changes over 30, 60, and 90 days with a consistent skincare routine like Trifecta.


























6 comments
Alba Lucia
Dr. Karam,
I’m on my second order of Trifecta. I’m already seen my skin lighter but sun/age spots haven’t faded yet.
I want to love your Trifecta but am finding an issue when I use tinted sun protection or try to use a light foundation and makeup. It’s like the Trifecta and the sunblock or foundation don’t mix well at all. As soon as I use sunblock or makeup over Trifecta, the products become like little balls and the skin looks terrible. I have to wet my fingers with water to try even out the products on my face. This never happened to me before.
I have used Dr. Obagi’s tinted sun protection, Algenist with no added color and Laura Mercier tinted moisturizer and the problem occurs with all of them. What could be happening? Please help me understand what might be happening because I want to love your products but not if I continue experiencing this problem . I look forward to hearing from you. Thank you.
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KaramMD Skin replied:
Hi Alba—Thanks for your comment! It’s important to remember that optimal results come with consistent use over 3–6 months while following the recommended dosage. Pilling can happen for several reasons. The most common is using too much product or layering too heavily. Try reducing the amount and applying each step in thin, even layers. Technique matters as well: rubbing too vigorously creates friction that leads to pilling. Instead, gently pat or press products into the skin using upward motions. Also be sure you’re cleansing thoroughly before applying the Trifecta. If you wear heavier makeup, a double cleanse can help remove residual buildup, which can also cause pilling. Feel free to reach out to our Customer Care team for more advice! 💞
Pascale
Hi
I’m 58 and as my friends and family say, I look younger than my age, even though I don’t use much skincare. But I suggest, I haven’t found the right one yet, especially for women in my age. Your products crossed my timeline and I would love to give them a try. My question: I’ve got freckles, which I love and would like to know, if using Trifeca would not only make the dark aging-spots dissapear, but also my freckles? Thank you very much for your answer.
Kind regards from Switzerland
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KaramMD Skin replied:
Hi Pascale—Thanks for your comment! It’s wonderful to hear that you’ve been told you look younger than your age, especially with a minimalist skincare routine. That’s a great foundation to build on! To answer your question: the Trifecta system is designed to support healthy skin renewal and even out tone by targeting discoloration, particularly age spots, sun damage, and post-inflammatory pigmentation. However, it’s not formulated to eliminate freckles specifically. Many of our customers who love their natural freckles find that Trifecta helps brighten and firm the skin overall, while still allowing their freckles to remain visible and intact. We’d love for you to give the Trifecta a try, and we offer a 60-day money-back guarantee so you can explore the products with peace of mind.
Kathy Elizeus
Question- I had a facelift by a very reputable surgeon-I look great, but can the same care be used for arms and crepey legs?
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KaramMD Skin replied:
Hi Kathy—Thanks for your comment! The same level of care can be applied to your arms and legs, but body skin takes longer to respond to anti-aging treatments than facial skin. A combination of body specific skincare, in-office treatments, and lifestyle adjustments will give you the best results.
Carol Kaye
This will sound unbelievable but wonderful! Pleased with positive skin in a month, .Pilates instructor, Senior, Personal Trainer age 77yrs
Young!!! Thanks for helping me look my be Best as I work 6 days e week ❤️🩹
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KaramMD Skin replied:
Hi Carol—Thank you for your comment! We’re glad to hear you’re looking and feeling great. Thank you for reading and please let us know if there’s ever a topic you’d like to see covered!
carmen lafountaine
Dr. Karam,
I’ve been a dedicated user of Skinceuticals C& E with ferulic, am, and tretinoin at night. Can your products be layered or should they be used on their own?
Thank you for sharing your knowledge and helping us on our skin care journey!
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KaramMD Skin replied:
Hi Carmen—Thanks for your questions. Trifecta covers all of your daily skincare needs. If you are not already religious with a Retinol, the Trifecta is perfect as a stand alone trio. While there won’t be any need for another product, you can continue using your Skinceuticals and Tretinoin if you’d like. You would simply apply any additional products after your Trifecta routine. Trifecta is meant to be used as a complete skincare system, so after you finish all three steps, you would apply your Tretinoin afterward as a supplement to the Retinol we already have in Illuminate. If you want to use your other Vitamin C alongside Quench, that should be fine. But pay attention to your skin to see if it’s too much—it’s essential to listen to your skin when layering products that have not been formulated to work together. We hope these guidelines help you, but if you have any further questions or need additional assistance, feel free to reach out to our customer care team at cusotmerservice@karammdskin.com <mailto:cusotmerservice@karammdskin.com>.
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