Get Smoother, Brighter Skin with Your Free Gift

For a limited time, receive a FREE full-size Polish Enzymatic Exfoliator with your new KaramMD Trifecta subscription.

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An image of a hand holding a polish enzymatic exfoliator skincare product.

Get Smoother, Brighter Skin with Your Free Gift

For a limited time, receive a FREE full-size Polish Enzymatic Exfoliator with your new KaramMD Trifecta subscription.

CLAIM MY FREE GIFT
An image of a hand holding a polish enzymatic exfoliator skincare product.

Why Exfoliation is a Must 

"Exfoliation is an essential part of skin management. The top layer of skin naturally builds up with dead skin cells, which causes dullness and roughness — but how you exfoliate matters. 

 

That's the idea behind Polish, our enzymatic exfoliator powered by papain and plant-based enzymes. Instead of physically scrubbing the skin, these enzymes gently digest dead skin cells, so even sensitive skin can use it without the abrasion or dryness that comes from traditional exfoliants. When used two to three times a week, Polish clears away that surface buildup, leaving skin feeling soft, bright, and remarkably smooth."  

 

Dr. Amir Karam

Founder, KaramMD Skin

Board Certified Facial Plastic Surgeon

Polish Preps. Trifecta Transforms.

Trifecta transforms your skin. Polish preps the way. Together, they deliver smoother, brighter, more radiant-looking skin.

Trifecta is a 3-step complete anti-aging skincare routine, including Rinse Cleanser, Quench Vitamin C Serum, and Illuminate Anti-Aging Treatment.

Polish is uniquely designed to gently, but effectively, exfoliate the skin.

When combined, the gentle exfoliation paired with powerful anti-aging actives will help give you your best skin ever.

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3 KaramMD Skincare products: Rinse Daily Cleanser, Quench Vitamin C Serum, and Illuminate Anti-Aging Cream.
KaramMD skincare products on a white background with text describing their uses. Rinse: Award winning cleanser to thoroughly purify and prep Quench: Antioxidant serum for deep cellular repair and hydration Illuminate: All-in-one anti-aging cream for visibly younger-looking skin
Three black KaramMD skincare bottles are shown against a light gray background with a white text panel above listing eight signs of aging and water droplets along the bottom.
Clinically Proven. Surprisingly Simple. "The KaramMD Trifecta was developed to solve a universal anti-aging issue: finding effective skincare that's both easy to use and delivers real, measurable results. I selected all 24 clinically proven active ingredients because I know they are the only answer to achieving lasting, youthful results. It's everything you need to achieve your absolute best skin." -Dr. Amir M Karam
Before and after comparison of skin texture with text indicating clinical improvement.
Trifecta is formulated with 24+ active ingredients for maximum results. Rinse: Aloe vera, arnica extract, willowherb extract Quench: Triple Vitamin C, Sodium Hyaluronate Glycerin Illuminate: Slow-Release Retinol, Niacinamide, Peptide & Lipid Complex
Promotional skincare graphic with text claiming clinically tested results and percentages for fine lines, wrinkles, hydration, and skin firmness, alongside a close-up of a woman's face with a white cream applied to her cheek.
A results timeline graphic for a skincare product titled 'When will I see results?'. It shows three side-profile photos of a woman's face at 4 weeks, 8 weeks, and 12+ weeks, with text listing expected improvements such as diminished fine lines, improved skin tone, and healthier skin.
Before-and-after skin comparison showing visible improvement in uneven skin tone over 8 weeks, with the text 'CLINICALS' at the top and close-up facial skin panels labeled BEFORE and AFTER 8 WEEKS.
KaramMD daily cleanser tube with text on a white background
Karam MD Quench Vitamin C Serum with product description on a white background
Karam MD Illuminate anti-aging cream bottle with product description on a white background
Get a $44 value welcome kit with your first subscription order of Trifecta! KaramMD skincare product set including bottles, pouches, and a booklet on a white background
A comparison infographic on a light gray background. The headline reads '24+ Active Ingredients.
A testimonial-style promotional graphic with a close-up of a woman's face on the right, showing closed eyes and a dollop of white cream on her cheek. On the left is large text reading '60 Days Down, Forever to Go!' and a customer quote attributed to LIZA.
A clean graphic on a light gray background showing three cream product dollops labeled Rinse, Quench, and Illuminate with text indicating usage amounts. No person, animal, or real environment is present, so this is not Lifestyle; it is an informational product graphic rather than a plain product shot, so Product/Packaging is the best fit.

KaramMD Trifecta

2,500+ Reviews

Experience the power of fewer steps and better results. Clinically proven to address wrinkles, elasticity, hydration, and tone, the KaramMD® Trifecta is a 3-step skincare system that delivers an unprecedented infusion of 24 active ingredients, formulated by the surgeon himself.

Picture of hand holding Polish Enzymatic exfoliator Picture of hand holding Polish Enzymatic exfoliator Picture of hand holding Polish Enzymatic exfoliator

Receive a FREE  

Full-Size Polish*

*With your New Trifecta Subscription. Offer ends l 11:59pm PST September 18, 2026.
Picture of hand holding Polish Enzymatic exfoliator

What's In Trifecta

  • Rinse Cleanser 2.5 fl oz., 75mL
    A non-foaming and antioxidant-rich gentle gel cleanser that helps maintain skin’s natural balance and purifies without stripping skin.
  • Quench Vitamin C Serum 1 fl oz., 30mL
    An antioxidant-packed formula that features three advanced, stable forms of Vitamin C to noticeably reduce the look of skin discoloration, protect against environmental stressors, and boost visible radiance—without any irritation.
  • Illuminate Anti-Aging Cream 1.7 fl oz., 50mL
    An all-in-one anti-aging formula that features encapsulated retinol, peptides, and antioxidants that targets fine lines and wrinkles, tone, texture, radiance, and pigmentation.

Surgeons Notes

“As we age, cell turnover slows down, which makes skin feel rougher, look duller, creates a barrier that prevents skincare products from working at their full potential. Polish is an at-home resurfacing treatment that removes those dry, dead skin cells and effectively boosts your Trifecta results.” —Dr. Amir Karam

How to Use

Trifecta is designed to be used twice daily, AM and PM. Add in Polish 1-3 times per week to enhance your results.

  1. Rinse: Use a dime-sized amount of product. Cleanse gently. Rinse face with warm warm removing product. Pat away excess water with your cotton towel.
  2.  Polish - Dispense 5-6 shakes of powder onto palm, then add a few drops of water to activate. Massage onto face, avoiding eye area. Leave for 3-5 minutes. Rinse clean. 
  3. Quench: Apply 1-2 pumps of the serum to slightly damp skin, covering your face, eyes, and neck.
  4. Illuminate: Follow immediately after Quench with 2-3 pumps, covering your entire face, eyes, and neck. Always follow with SPF in the morning.

Why do I need both Polish and Trifecta? 

Polish clears away dry, dull surface cells to support natural cell turnover—revealing smoother, brighter skin while helping you get the most from every Trifecta step. 

Trifecta helps visibly improve fine lines and wrinkles, improve the appearance of skin discoloration, and helps improve skin barrier function - all in 3 simple steps.

When will I see results? 

Did you know? It takes 28-days for skin cells to turn over, meaning significant improvements in texture, tone, and radiance builds over 30–90 days of consistent daily use. 

Why Your Best Skin Starts with Polish Enzymatic Exfoliator

Buffs away buildup for improved absorption of active ingredients

Clears away dry, dull surface cells to boost radiance and luminosity

Smooths rough skin and minimizes the appearance of pores

Supports natural cell turnover for improved skin texture and tone

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Real People, Real Reviews

Powerful, Proven Ingredients in Polish

Why Polish Enzymatic Exfoliator Stands Out from the Rest

Papain and Bromelain Fruit Enzymes

Help dissolve dry, dead skin cells

Rice, Coconut Milk, Bamboo, and Matcha Powders

Gently buff away rough patches, dull skin, and impurities

Azelaic Acid

Helps even skin tone and promotes clear skin

Panthenol

Soothes skin and improves texture
 

START YOUR ROUTINE

Your Best Skin Starts with Polish and Trifecta

Step 1:

Rinse Gentle Cleanser

Cleanses without stripping, maintaining your skin's natural balance.

Step 2:

Polish Enzymatic Exfoliator

Gently lifts away dead skin cells with fruit enzymes and aselaic acid, prepping skin for maximum absorption of active ingredients. 

Step 3:

Quench Vitamin C Serum

Brightens dull skin with three stable forms of Vitamin C that support your natural collagen production.

Step 4:

Illuminate Anti-Aging Treatment

Smooths fine lines and wrinkles with slow-release retinol and 20+ targeted actives, helping you look as young as you feel. 

START YOUR ROUTINE

Clinically Proven to Transform Your Skin

After 8 Weeks of Using KaramMD Trifecta:*

Title

100%

of subjects showed improvement in fine lines & wrinkles

91%

of subjects showed improvement in skin firmness

After 4 Weeks of Using Polish:*

Title

100%

of subjects noticed visible improvement in skin texture

100%

of subjects agree skin felt smoother

START YOUR ROUTINE

*Data on file at KaramMD Skin.

Faq

Are there any clinical studies around Trifecta?

Yes. Trifecta underwent rigorous third-party clinical testing - you can see the results of that on our Clinical Studies page.

Why should I use polish and trifecta together?

Every great routine starts with great prep. Polish buffs away buildup and gently resurfaces to reveal smoother, brighter, and perfectly prepped skin—so you get the most out of every step in your Trifecta routine.

How long does it take to see results with trifecta?

It takes 28-days for skin cells to turn over, which means in order to see a difference in your skin, you need to use them consistently for at least a month. That being said, significant improvements, encompassing texture, tone, and overall radiance, manifest with consistent application over an extended period, typically spanning 3 to 6 months. 

is polish a powder?

Yes, Polish starts as a powder to preserve efficacy. To activate Polish, dispense about 5-6 shakes into your palm, add a small amount of water, and put the paste directly on your face. Leave on for 3-5 minutes for real results!

How often should i use each product?

Polish should only be used 1-3 times per week. Trifecta should be used consistently, morning and evening, every day for the best results.

START MY ROUTINE