01.
Retinol - 10/10
If I could recommend only one anti-aging skincare ingredient, it would probably be retinol.
Very few ingredients have the level of scientific evidence behind them that retinol does. It stimulates collagen, improves skin texture, softens fine lines, helps with pigmentation, and even improves acne.
It’s one of the true foundational ingredients in skincare.
The biggest issue is irritation. A lot of people try retinol, overdo it, get inflamed, and quit too early. That’s actually one of the reasons I developed the KaramMD Trifecta system. I wanted patients to be able to use powerful active ingredients consistently without constantly battling irritation and barrier damage.
Because consistency matters more than intensity.


























15 comments
Karen Minerva
Please sign me up to join Mailing list thank you !
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KaramMD Skin replied:
Hi Karen—Thanks for your comment! You can sign up to join our mailing on our website. If you run into any trouble please reach out to our customer care team!
Jazmin Johnson
Thank you so much for this information I really appreciate you taking the time to give us all of these great recommendations on skin treatments, I hope one day my piggy bank ☺️gets full enough to make it to your office 😊meanwhile I will continue to follow your advice on how to improve my skin! Muchas gracias 💜you are the best 🤗🤗
Susie Foreman
I buy Retinol A in Mexico when I travel there. What percentage is the best? Isn’t Retinol stronger when you by it in Mexico than what you get in the US.
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KaramMD Skin replied:
Hi Susie—Thanks for your question! Dr. Karam doesn’t think the concentration (or percentage) is the most important thing to consider. It’s more important that you find a Retinol that you can use consistently without irritation. Ultimately, the best product is the one you can use every day for an extended period of time.
Dawn
Hi, thank you for the update. Which collagen supplement do you recommend as their is so much on the market .
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KaramMD Skin replied:
Hi Dawn—Thanks for your comment! Dr. Karam doesn’t recommend a specific collagen supplement. When shopping for collagen, prioritize hydrolyzed collagen peptides for optimal absorption. Look for targeted, clean formulas backed by third-party testing to ensure purity and effectiveness.
Alyssa Brennan Brennan
Thank you for this article. Id like the next one to cover Ultherapy, Thermage anc any/all skin tightening type devices
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KaramMD Skin replied:
Hi Alyssa — Thank you for your comment and for the suggestion! We’ll make sure to pass this along to the team as a future Journal topic. In the meantime, you may find his existing articles on energy devices and skin laxity a helpful starting point: https://karammdskin.com/blogs/expert-advice/
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