KaramMD Trifecta
The Complete Anti-Aging Routine
The KaramMD Trifecta is a simple skincare system proven to give you healthier, younger-looking skin in 3 easy steps—formulated to target all aspects of aging skin simultaneously.
For a limited time, Trifecta subscriptions will also receive:
+ 1 FREE travel-sized EltaMD sunscreen
+ 1 FREE limited-edition KaramMD hat
We'll deliver your product every:
Modify or Cancel your Subscription at any time
✓ 60 day money back guarantee
✓ FREE SHIPPING to USA, Canada, and UK
PRODUCT OVERVIEW
The KaramMD Trifecta is an innovative, clinically proven skincare approach. It consolidates up to 10 product categories into a 3 step routine, making it easy to stay consistent and see results.
Make sure to make sure to use Trifecta consistently twice a day for at least a month to see results. This is critical because it takes 28-days for skin cells to turn over. Significant improvements in texture, tone, and radiance show after 3-6 months.
Skincare doesn’t need to be complicated and the Trifecta offers you a proven path on your journey to great skin.
Size:
- Rinse 2.5 fl oz 75 mL
- Quench 1 fl oz 30 mL.
- Illuminate 1.7 fl oz 50 mL
KEY INGREDIENTS
Aloe Vera: Soothes discomfort and hydrates skin.
Apple Amino Acids: Cleanse without stripping natural oils.
Arnica Extract: Calms irritation and reduces redness.
Broccoli Seed Oil: Supports skin barrier for moisture.
Willowherb Extract: Provides antioxidant protection.
Allantoin: Naturally exfoliates and reduces redness
Triple Vitamin C: Lightens dark spots & boosts natural glow.
Sodium Hyaluronate: Deeply hydrates and plumps skin.
Green Tea: Antioxidant protection and calms irritation.
Willowherb: Balances oil production and calms redness.
Licorice Root: Brightens skin and reduces discoloration.
Panthenol: Stimulates collagen production & skin repair.
Aloe: Hydrates, soothes, and helps reduce skin irritation.
Vitamin E: Strengthens defenses against premature aging.
Encapsulated Retinol: Works deeply to reduce fine lines and wrinkles.
Niacinamide: Balances skin tone and refines texture.
Peptide Complex: Supports the natural repair process.
Lipid Complex: Enhances elasticity and skin barrier.
Sodium Hyaluronate: Boosts hydration to reduce fine lines.
Botanical Lighteners: Naturally reduce pigmentation.
Edelweiss Flower Extract: Firms and protects skin.
Squalene: Strengthens the barrier and locks in moisture.
Hibiscus Flower: Supports body’s natural growth factors
Vitamin C & E: Antioxidants for skin protection and repair.
A LETTER FROM OUR FOUNDER
It's More Than Skincare.
We are a Community.
At KaramMD, our mission is to guide you at every stage of your journey to healthier, more radiant skin. Not just with proven skincare, but with the knowledge, tools, and support to help you succeed.
To celebrate Love Your Skin Day, and to help you protect your progress during these sunny summer months, I’m adding a complimentary sun protection bundle when you subscribe to Trifecta.
But this is about more than just shielding your skin. It’s about showing up for yourself, your routine, and the belief that caring for your skin can transform how you feel, inside and out.
That’s why I created this gift. My hope is for our community to show the world you’re part of something bigger—a movement to simplify skincare, build confidence, and celebrate consistent, meaningful progress towards looking as good as you feel.
Thank you for being part of this. You inspire everything we do.
A LETTER FROM OUR FOUNDER
It's More Than Skincare.
We are a Community.
At KaramMD, our mission is to guide you at every stage of your journey to healthier, more radiant skin. Not just with proven skincare, but with the knowledge, tools, and support to help you succeed.
To celebrate Love Your Skin Day, and to help you protect your progress during these sunny summer months, I’m adding a complimentary sun protection bundle when you subscribe to Trifecta.
But this is about more than just shielding your skin. It’s about showing up for yourself, your routine, and the belief that caring for your skin can transform how you feel, inside and out.
That’s why I created this gift. My hope is for our community to show the world you’re part of something bigger—a movement to simplify skincare, build confidence, and celebrate consistent, meaningful progress towards looking as good as you feel.
Thank you for being part of this. You inspire everything we do.
How to Use
Rinse: Apply to wet skin, massage in circular motions, then rinse clean.
Quench: Apply 2 pumps to slightly damp face, eye area, and neck.
Illuminate: Apply 3 pumps to face, eye area, and neck.
Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.
HOW TO USE: TRIFECTA ROUTINE
How to Use
Rinse: Apply to wet skin, massage in circular motions, then rinse clean.
Quench: Apply 2 pumps to slightly damp face, eye area, and neck.
Illuminate: Apply 3 pumps to face, eye area, and neck.
Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.
HOW TO USE: TRIFECTA ROUTINE
Clinically Proven to Fight Aging Skin
The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:
100% of subjects had improvement in skin’s moisture.
100% of subjects had improvement in fine lines & wrinkles.
91% of subjects had improvement in skin’s firmness.
Clinically Proven to Fight Aging Skin
The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:
100% of subjects had improvement in skin’s moisture.
100% of subjects had improvement in fine lines & wrinkles.
91% of subjects had improvement in skin’s firmness.
Join Thousands of Subscribers
Truly Innovative
Anti-Aging Formulas
1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.
2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.
3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.
Truly Innovative
Anti-Aging Formulas
1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.
2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.
3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.
Great Skin Made Simple
The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta.
Great Skin Made Simple
The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta.
Skincare Advice You Can Trust
The Best Anti-Aging Ingredients
When assessing your skincare products, it is essential they include the following anti-aging ingredients. Each of these ingredients play a unique role in skin health and are crucial to achieving y...
Dr. Karam's Philosophy for an Effective Skincare Routine
I believe I’ve finally found the secret to anti-aging. After 20 years of experience—and a lot of patience (and patients) throughout my career—I came to understand that skincare is more than just t...
Trifecta 101: What You Need to Know When Starting Your New Skincare Routine
Whether you’re completely new to skincare or transitioning to the Trifecta system, this guide will walk you through what to expect as you begin your skincare journey.
INGREDIENTS
RINSE
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
QUENCH
Aqua/Water/Eau, Pentylene Glycol, Magnesium Ascorbyl Phosphate, Aminopropyl Ascorbyl Phosphate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Ziziphus Spina-Christi (Christ’s Thorn) Leaf Extract, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Camellia Sinensis (Tea Camellia) Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Trehalose, Panthenol, Aloe Barbadensis (Aloe Vera) Leaf Juice, Tocopherol, Glycerin, Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Sodium Nitrate, Disodium Phosphate, Polysorbate 60, Citric Acid, Sodium Phosphate, Potassium Sorbate, PPG-26-Buteth-26, Sodium Benzoate, PEG-40 Hydrogenated Castor Oil, Glyoxal, Sodium Metabisulfite, Sodium Hydroxide.
ILLUMINATE
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Caprylic/Capric Triglyceride, Glycerin, Jojoba Oil/Macadamia Seed Oil Esters, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, Coco-Caprylate/Caprate, Dimethicone, Niacinamide, Cetearyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Glucoside, Brassica Oleracea Italica (Broccoli) Seed Oil, Retinol, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Phytosterols, 3-O-Ethyl Ascorbic Acid, Potassium Azeloyl Diglycinate, Leontopodium Alpinum Callus Culture Extract, Squalane, Phytosteryl Macadamiate, Hibiscus Abelmoschus (Musk Okra) Extract, Bellis Perennis (Daisy) Flower Extract, Calendula Officinalis (Marigold) Flower Extract*, Hexylresorcinol, Arnica Montana (Mountain Arnica) Flower Extract, Melissa Officinalis (Lemon Balm) Leaf Extract, Oryza Sativa (Rice) Extract, Leuconostoc Ferment Filtrate, Superoxide Dismutase, Soybean Peroxidase, Tocopherol, Cetyl alcohol, Phenoxyethanol, Biosaccharide Gum-1, Glyceryl Stearate, PEG-100 Stearate, Ceteareth-20, Butylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Polysorbate 60, Sorbitan Isostearate, Xanthan Gum, PEG-20, Sucrose Palmitate, Sucrose Tristearate, Tocopheryl Acetate, Glyceryl Linoleate, Alcohol Denat., Phenethyl Alcohol, Disodium Phosphate, Citric Acid, Potassium Sorbate, Sodium Hydroxide, Iodopropynyl Butylcarbamate, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
Aqua/Water/Eau, Pentylene Glycol, Magnesium Ascorbyl Phosphate, Aminopropyl Ascorbyl Phosphate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Ziziphus Spina-Christi (Christ’s Thorn) Leaf Extract, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Camellia Sinensis (Tea Camellia) Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Trehalose, Panthenol, Aloe Barbadensis (Aloe Vera) Leaf Juice, Tocopherol, Glycerin, Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Sodium Nitrate, Disodium Phosphate, Polysorbate 60, Citric Acid, Sodium Phosphate, Potassium Sorbate, PPG-26-Buteth-26, Sodium Benzoate, PEG-40 Hydrogenated Castor Oil, Glyoxal, Sodium Metabisulfite, Sodium Hydroxide.
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Caprylic/Capric Triglyceride, Glycerin, Jojoba Oil/Macadamia Seed Oil Esters, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, Coco-Caprylate/Caprate, Dimethicone, Niacinamide, Cetearyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Glucoside, Brassica Oleracea Italica (Broccoli) Seed Oil, Retinol, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Phytosterols, 3-O-Ethyl Ascorbic Acid, Potassium Azeloyl Diglycinate, Leontopodium Alpinum Callus Culture Extract, Squalane, Phytosteryl Macadamiate, Hibiscus Abelmoschus (Musk Okra) Extract, Bellis Perennis (Daisy) Flower Extract, Calendula Officinalis (Marigold) Flower Extract*, Hexylresorcinol, Arnica Montana (Mountain Arnica) Flower Extract, Melissa Officinalis (Lemon Balm) Leaf Extract, Oryza Sativa (Rice) Extract, Leuconostoc Ferment Filtrate, Superoxide Dismutase, Soybean Peroxidase, Tocopherol, Cetyl alcohol, Phenoxyethanol, Biosaccharide Gum-1, Glyceryl Stearate, PEG-100 Stearate, Ceteareth-20, Butylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Polysorbate 60, Sorbitan Isostearate, Xanthan Gum, PEG-20, Sucrose Palmitate, Sucrose Tristearate, Tocopheryl Acetate, Glyceryl Linoleate, Alcohol Denat., Phenethyl Alcohol, Disodium Phosphate, Citric Acid, Potassium Sorbate, Sodium Hydroxide, Iodopropynyl Butylcarbamate, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
Frequently Asked Questions
Our caring team of experts has the answers.
How frequently should I be using the Trifecta?
All products should be used twice a day, every day. Adherence to the recommended dosage of twice a day, every day, is paramount. The efficacy of the Trifecta regimen is well-documented in our clinicals, but success hinges on your unwavering dedication. Skipping even a few days can compromise the synergistic effects of the Trifecta regimen, necessitating a reset and extending the timeline to witness desired results.
Do I need different products morning & night?
We believe that cleansing & moisturizing properly are all that is needed to protect your skin from external stressors. The ingredient deck in all three products has been strategically designed to benefit you both am & pm with no need to switch, add or omit products.
How long does the Trifecta last?
The Trifecta should last you around 30 days across all products if using them twice a day as recommended.
Do I need sunscreen with the Trifecta?
Yes! Sunscreen should be part of any daily routine.
When will I see results with the Trifecta?
It takes 28-days for skin cells to turn over, which means in order to see a difference in your skin from KaramMD products, you need to use them consistently for at least a month. That being said, significant improvements, encompassing texture, tone, and overall radiance, manifest with consistent application over an extended period, typically spanning 3 to 6 months. Adherence to the recommended dosage of twice a day, every day, is paramount.
This product is rated 4.7 of 5.0 stars.
It has received 1409 reviews.
- SSharman9 hours agoRated 5 out of 5 stars5 Stars
Really love this trifecta. Soooo easy. I have seen improvement after a month of disciplined use. All other products cluttering my space has gone to goodwill.
- CCherylYesterdayRated 5 out of 5 stars5 Stars
Love the product! Packaged well! Arrived quickly.
- SSafuraVerified Buyer2 days agoRated 5 out of 5 starsTrifecta
I’ve been using Dr. Amir Karam’s skincare line for six months now, and I can honestly say it’s been a game-changer. I use it every day, twice a day, without fail—and the results speak for themselves. At 52, I receive more compliments on my skin than ever before. People constantly tell me I look refreshed and glowing.
I’ve always taken care of myself—healthy diet, regular exercise, no smoking or drinking, religious about SPF, and I avoid sun exposure as much as possible. And like many others, I’ve spent a lot of money over the years trying every skincare brand under the sun. But nothing gave me the consistent, noticeable results I was looking for.
Then I came across Dr. Karam’s page. What he said made so much sense—why buy so many separate products when one well-designed system could do it all? I decided to invest in a monthly subscription and commit to his system, and I’m so glad I did.
This isn’t just skincare—it’s skincare that delivers. My skin feels healthier, looks brighter, and I genuinely feel more confident. I’m so happy with the results and just wanted to share my experience with anyone who's considering it. It's worth every penny.
KSKaramMD SkinYesterdayWow — thank you so much for this amazing review! We’re genuinely blown away, and can we just say… 52?! You look absolutely incredible! Your skin is glowing, radiant, and honestly, you don’t look anywhere near your age. Whatever you’re doing—with your lifestyle, your dedication, and your commitment to this routine—it’s clearly working, and we’re so thrilled that Dr. Karam’s system could be part of that magic.
It’s stories like yours that truly light us up. We know how overwhelming the world of skincare can be, so hearing that our simple, effective system has finally given you the consistent results you were searching for means everything. Thank you for trusting us, for sticking with it, and for sharing your experience so generously. You’re the perfect example of how powerful great skincare + self-care can be. Keep glowing—you’re an inspiration! ✨
- MMelissa3 days agoRated 5 out of 5 stars5 Stars
Aside from what it does for my skin, only 3 products to use is just the best!