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4.7
Rated 4.7 out of 5 stars
1,622 Reviews

The KaramMD Trifecta is a simple skincare system proven to give you healthier, younger-looking skin in 3 easy steps—formulated to target all aspects of aging skin simultaneously.

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MD Formulated

Clinically Proven

Premium Ingredients

For All Skin Types

Cruelty Free

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

Read the KaramMD Journal

Skincare Advice You Can Trust

The Best Anti-Aging Ingredients

The Best Anti-Aging Ingredients

When assessing your skincare products, it is essential they include the following anti-aging ingredients. Each of these ingredients play a unique role in skin health and are crucial to achieving y...

Dr. Karam's Philosophy for an Effective Skincare Routine

Dr. Karam's Philosophy for an Effective Skincare Routine

I believe I’ve finally found the secret to anti-aging. After 20 years of experience—and a lot of patience (and patients) throughout my career—I came to understand that skincare is more than just t...

KaramMD Trifecta skincare routine: Rinse Daily Cleanser, Quench Vitamin C Serum, and Illuminate Anti-Aging Cream held in a single hand.

Trifecta 101: What You Need to Know When Starting Your New Skincare Routine

Whether you’re completely new to skincare or transitioning to the Trifecta system, this guide will walk you through what to expect as you begin your skincare journey.

INGREDIENTS

Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.

*Organic Ingredient

Frequently Asked Questions

Our caring team of experts has the answers.

4.7
Rated 4.7 out of 5 stars
Based on 1,622 reviews
Slide 1 selected
1,622 reviews
  • JD
    Jill D.
    Verified Buyer
    What are your skin concerns? Fine Lines & Wrinkles
    18 seconds ago
    What are your skin concerns? Fine Lines & Wrinkles
    Rated 5 out of 5 stars
    Best Skincare

    The Trifecta skincare routine has simplified my routine with a system that incorporates every product your skin needs in one simple routine. Dr Karam has put together a perfect system that has my skin looking and feeling younger with each week i have been using it. In the past I have spent thousands on different products all claiming to be the answer. THIS is the answer. Thank you Dr. Karam!

  • JS
    Jill S.
    Verified Buyer
    What are your skin concerns? Fine Lines & Wrinkles, General Aging, Loss of Elasticity , Skin Texture , Sensitivity
    20 hours ago
    What are your skin concerns? Fine Lines & Wrinkles, General Aging, Loss of Elasticity , Skin Texture , Sensitivity
    Rated 5 out of 5 stars
    Amazing products

    I ahve been using Trigecta for over a year. I love the easy quick applications not to mention how good my skin looks and feels.

    Highly recommend to treat yourself as your ne k and.face deserves it!🤍

  • IC
    Isabelle C.
    Verified Buyer
    What are your skin concerns? Environmental Damage, Sensitivity , Fine Lines & Wrinkles
    Yesterday
    What are your skin concerns? Environmental Damage, Sensitivity , Fine Lines & Wrinkles
    Rated 5 out of 5 stars
    It works!

    I was researching and hunting for skincare products with active ingredients for my sensitive, aging skin. It became my mission and soon obsession and I ended up with too many different products that completely overwhelmed me, not to mention overloaded my sensitive skin. Even though I carefully selected clean ingredients and stayed away from any ingredients that I know I’m allergic to, my rosacea flared up so I stopped using all of them.

    When I came across Dr. Karam on YouTube, I was very intrigued because of his educational intentions. Because I agree with his skincare principles, I felt comfortable trying the Trifecta. The fact that he personally curated active ingredients and that the regimen is simple were the major selling points for me.

    Fast forward 18 months, my sun spots are less noticeable now and my skin looks great. Would love to visit him for his vertical lift one day but until then, I have Trifecta.

  • JP
    Judy P.
    Verified Buyer
    What are your skin concerns? Fine Lines & Wrinkles, General Aging
    Yesterday
    What are your skin concerns? Fine Lines & Wrinkles, General Aging
    Rated 5 out of 5 stars
    Effective and Simple

    Over the years we have all waisted hundreds of dollars on skincare that never got used up. Not now , I use each item and have the need to buy my next trifecta as I do see results. I have been using Dr. KaramMD for over three years and will continue. Simple and effective. What more could I ask for.