KaramMD Trifecta

The Complete Anti-Aging Routine

4.7
Rated 4.7 out of 5 stars
1,731 Reviews

The KaramMD Trifecta is a simple skincare system proven to give you healthier, younger-looking skin in 3 easy steps—formulated to target all aspects of aging skin simultaneously.

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MD Formulated

Clinically Proven

Premium Ingredients

For All Skin Types

Cruelty Free

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Key Ingredients

Rinse Daily Cleanser
  • Aloe Vera: Soothes discomfort and hydrates skin
  • Apple Amino Acids: Cleanse without stripping natural oils
  • Arnica Extract: Calms irritation and reduces redness
  • Broccoli Seed Oil: Supports skin barrier for moisture
  • Willowherb Extract: Provides antioxidant protection
  • Allantoin: Naturally exfoliates and reduces redness

View all ingredients
Quench Vitamin C Serum
  • Triple Vitamin C: Lightens dark spots & boosts natural glow
  • Sodium Hyaluronate: Deeply hydrates and plumps skin
  • Green Tea: Antioxidant protection and calms irritation
  • Willowherb: Balances oil production and calms redness
  • Licorice Root: Brightens skin and reduces discoloration
  • Panthenol: Stimulates collagen production & skin repair
  • Aloe: Hydrates, soothes, and helps reduce skin irritation
  • Vitamin E: Strengthens defenses against premature aging
View all ingredients
Illuminate Anti-Aging Cream
  • Encapsulated Retinol: Works deeply to reduce fine lines and wrinkles
  • Niacinamide: Balances skin tone and refines texture
  • Peptide Complex: Supports the natural repair process
  • Lipid Complex: Enhances elasticity and skin barrier
  • Sodium Hyaluronate: Boosts hydration to reduce fine lines
  • Botanical Lighteners: Naturally reduce pigmentation
  • Edelweiss Flower Extract: Firms and protects skin
  • Squalene: Strengthens the barrier and locks in moisture
  • Hibiscus Flower: Supports body’s natural growth factors
  • Vitamin C & E: Antioxidants for skin protection and repair

View all ingredients

Put Your Routine on Autopilot

  • Stay Stocked

    Automatic delivery means you’ll never run out or lose momentum.

  • Stay Consistent

    Use morning and night without interruption for clinically proven improvement.

  • See Results

    Save 20% on every order and enjoy exclusive perks that reward your commitment.

SUBSCRIBE TO TRIFECTA

WHY CONSISTENCY IS KEY

Skincare works like fitness: The more consistent you are, the stronger your results become. Every day you commit to your routine, your skin gets healthier, brighter, and more resilient.

Consistency chart showing improvement over months

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

Read the KaramMD Journal

Skincare Advice You Can Trust

Best anti-aging skincare ingredients to try

The Best Anti-Aging Ingredients

When assessing your skincare products, it is essential they include the following anti-aging ingredients. Each of these ingredients play a unique role in skin health and are crucial to achieving y...

Dr. Amir Karam, founder of Karam MD Skincare

Dr. Karam's Philosophy for an Effective Skincare Routine

I believe I’ve finally found the secret to anti-aging. After 20 years of experience—and a lot of patience (and patients) throughout my career—I came to understand that skincare is more than just t...

KaramMD Trifecta skincare routine: Rinse Daily Cleanser, Quench Vitamin C Serum, and Illuminate Anti-Aging Cream held in a single hand.

Trifecta 101: What You Need to Know When Starting Your New Skincare Routine

Whether you’re completely new to skincare or transitioning to the Trifecta system, this guide will walk you through what to expect as you begin your skincare journey.

All Ingredients

The Most Powerful Anti-Aging Ingredients All In One System

INGREDIENTS GLOSSARY

Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.*Organic Ingredient

Frequently Asked Questions

Our caring team of experts has the answers.

4.7
Rated 4.7 out of 5 stars
Based on 1,731 reviews
Slide 1 selected
1,731 reviews
  • LS
    Linda S.
    Verified Buyer
    What are your skin concerns? Fine Lines & Wrinkles, General Aging, Uneven Skin Tone / Discoloration , Loss of Elasticity , Congested Pores
    22 seconds ago
    What are your skin concerns? Fine Lines & Wrinkles, General Aging, Uneven Skin Tone / Discoloration , Loss of Elasticity , Congested Pores
    Rated 5 out of 5 stars
    2 weeks in an I noticed a difference!

    I have tried so many products from different companies….drug store brands to high end. It was taking too much mental energy figuring out which serum to use when and what would really work with only minimal results. That’s what led me to Trifecta. The simplicity of the system with great ingredients from a well respected doctor. Just two weeks in and I surprisingly noticed a difference! My skin was more even and bright. 4 weeks in and it’s more firm feeling. Trifecta is quick and easy to use. I’m looking forward to future improvement and will continue using this system!

  • TP
    Tracey P.
    Verified Buyer
    What are your skin concerns? Congested Pores , Fine Lines & Wrinkles, General Aging
    3 hours ago
    What are your skin concerns? Congested Pores , Fine Lines & Wrinkles, General Aging
    Rated 5 out of 5 stars
    Wow

    This trio is amazing! I see and feel the difference! The company was easy to communicate with when I had a question.

  • D
    Dara
    23 hours ago
    Rated 5 out of 5 stars
    5 Stars

    It works!!

  • B
    Brandy
    Yesterday
    Rated 5 out of 5 stars
    5 Stars

    I tried to break away from this line..... and I came crawling back. Its just lovely.