KaramMD Trifecta

The Complete Anti-Aging Routine

4.7
Rated 4.7 out of 5 stars
1,361 Reviews

A simple skincare system proven to give you healthier, younger-looking skin in 3 easy steps—formulated with powerful active ingredients to target all aspects of aging skin simultaneously.

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MD Formulated

Clinically Proven

Premium Ingredients

For All Skin Types

Cruelty Free

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

Read the KaramMD Journal

Skincare Advice You Can Trust

The Best Anti-Aging Ingredients

The Best Anti-Aging Ingredients

When assessing your skincare products, it is essential they include the following anti-aging ingredients. Each of these ingredients play a unique role in skin health and are crucial to achieving y...

Dr. Karam's Philosophy for an Effective Skincare Routine

Dr. Karam's Philosophy for an Effective Skincare Routine

I believe I’ve finally found the secret to anti-aging. After 20 years of experience—and a lot of patience (and patients) throughout my career—I came to understand that skincare is more than just t...

KaramMD Trifecta skincare routine: Rinse Daily Cleanser, Quench Vitamin C Serum, and Illuminate Anti-Aging Cream held in a single hand.

Trifecta 101: What You Need to Know When Starting Your New Skincare Routine

Whether you’re completely new to skincare or transitioning to the Trifecta system, this guide will walk you through what to expect as you begin your skincare journey.

INGREDIENTS

Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.

*Organic Ingredient

Frequently Asked Questions

Our caring team of experts has the answers.

4.7
Rated 4.7 out of 5 stars
Based on 1,361 reviews
1,361 reviews
  • T
    Tom
    Verified Buyer
    22 hours ago
    Rated 5 out of 5 stars
    50 year old man

    After years of working outside in the sun, shade, cold and hot climates I am afraid I have done irreversible damage but after using trifecta for 30-40 days I have noticed a huge difference in how my face feels. So healthy and rejuvenated. Even if I do not see a big difference in 3-6 months the healthy feeling that this leaves my face with is worth the price. Should I use any of the other products for added benefit? Dumb construction guy question.

    KS Profile picture for KaramMD Skin
    KaramMD Skin
    5 minutes ago

    Thank you for your wonderful review, Tom! We're absolutely thrilled to hear about your experience with the Trifecta system, especially given your history of working in challenging outdoor conditions. It's particularly rewarding to hear how your skin feels healthier and more rejuvenated - that sensation of skin wellness is such an important indicator that your skin barrier is being properly supported. As someone who has spent years working in various weather conditions, your feedback is especially valuable and meaningful to us. The fact that you're already seeing and feeling significant improvements in just 30-40 days is fantastic, and we're excited for you to experience even more positive changes in the months ahead.

    There are no dumb questions (from construction guys or otherwise)! Enrich and Polish are definitely a great supplement to your routine if you feel like taking things to the next level. Polish is great for maintaining healthy and vibrant skin. It addresses the accumulation of dry skin on the surface layer of the skin which inhibits the natural process of cell turnover. Exfoliation helps to address these concerns by sloughing off the dead skin cells, allowing the new and healthy skin cells to surface. This process not only fights dullness, but promotes a cleaner, fresher appearance as it uncovers the youthful and radiant skin beneath. Regular exfoliation can also improve the efficacy of other skincare products by ensuring better absorption into the skin.

    Enrich Breathable Barrier Balm adds some extra moisture, seals the skin to decrease nightly evaporative loss, while simultaneously strengthening the lipid profile and skin barrier function, which is essential to healthy, youthful-looking skin. You can always reach out to us if you have any additional questions!

    Your trust in our products means the world to us, and we're deeply grateful to have you as part of the KaramMD Skin community. Thank you for sharing your inspiring experience with us!

  • I
    Ingrid
    Verified Buyer
    2 days ago
    Rated 4 out of 5 stars
    Feels good on skin

    I am new to this product. It feels good on my skin and I intend to continue using it.

    KS Profile picture for KaramMD Skin
    KaramMD Skin
    1 minute ago

    Thank you for sharing your thoughtful feedback, Ingrid! We're pleased to hear about your initial positive experience with Trifecta and that you're noticing how well it feels on your skin.

    As you're new to the product, you're at the beginning of your skincare journey with us. Many of our clients find that while the immediate sensation on the skin is pleasant, the most noticeable improvements become visible after several months of consistent use, as this allows time for the active ingredients to work with your skin's natural renewal cycle.

    Our clinically-proven formula is designed to deliver progressive results that build over time, particularly as the ingredients work synergistically to support your skin's needs. We're encouraged by your intention to continue using Trifecta, as consistency is key to achieving optimal results.

    We're honored to be part of your skincare journey and look forward to supporting you as you continue to experience the benefits of Trifecta in your daily routine.

  • LG
    Lisa G.
    Verified Buyer
    2 days ago
    Rated 5 out of 5 stars
    Love it!

    I think it works so well that I recommend it to my patients every day!

    KS Profile picture for KaramMD Skin
    KaramMD Skin
    16 seconds ago

    Thank you for your wonderful review, Lisa G! We're absolutely thrilled to hear that you're not only loving the Trifecta system but also recommending it to your patients - that's incredibly meaningful to us. As a healthcare professional, your endorsement carries special weight, and we're honored to have earned your trust. Your confidence in our products means the world to us, and we're deeply grateful to have you as part of the KaramMD Skin community. Thank you for sharing your experience and for helping others discover the transformative benefits of our skincare system!

  • I
    Inna
    2 days ago
    Rated 5 out of 5 stars
    5 Stars

    Amazing skin care that is easy to use and reaps great results if ised consistently!