KaramMD Trifecta

The Complete Anti-Aging Routine

4.7
Rated 4.7 out of 5 stars
1,254 Reviews

The KaramMD Trifecta is an all-in-one skincare system designed to simplify your routine while delivering maximum results. This 3-step routine targets every sign of aging—reducing fine lines and wrinkles, smoothing skin texture, balancing skin tone, and boosting brightness for a healthy, youthful glow.

Ready to take the first step toward radiant, youthful skin? Now’s your chance.

For a limited time, subscribe to Trifecta and a free Enrich Balm. No code needed--your gift will be added to your cart automatically with any new 30 or 45 day day subscription.

refresh icon

We'll deliver your product every:

Modify or Cancel your Subscription at any time

✓ 60 day money back guarantee

✓ FREE SHIPPING to USA, Canada, and UK

MD Formulated

Clinically Proven

Premium Ingredients

For All Skin Types

Cruelty Free

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

Read the KaramMD Journal

Skincare Advice You Can Trust

The Best Anti-Aging Ingredients

The Best Anti-Aging Ingredients

When assessing your skincare products, it is essential they include the following anti-aging ingredients. Each of these ingredients play a unique role in skin health and are crucial to achieving y...

Dr. Karam's Philosophy for an Effective Skincare Routine

Dr. Karam's Philosophy for an Effective Skincare Routine

I believe I’ve finally found the secret to anti-aging. After 20 years of experience—and a lot of patience (and patients) throughout my career—I came to understand that skincare is more than just t...

KaramMD Trifecta skincare routine: Rinse Daily Cleanser, Quench Vitamin C Serum, and Illuminate Anti-Aging Cream held in a single hand.

Trifecta 101: What You Need to Know When Starting Your New Skincare Routine

Whether you’re completely new to skincare or transitioning to the Trifecta system, this guide will walk you through what to expect as you begin your skincare journey.

INGREDIENTS

Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.

*Organic Ingredient

Frequently Asked Questions

Our caring team of experts has the answers.

4.7
Rated 4.7 out of 5 stars
Based on 1,254 reviews
1,254 reviews
  • JP
    Jennifer P.
    Verified Buyer
    14 seconds ago
    Rated 5 out of 5 stars
    Incredible moisture!

    I just completed my first month using trifecta and I’m definitely noticing so much more moisture in my skin. It feels so much more healthy and plump. I’m looking forward to the ongoing benefits! I also enjoy the email updates. I get along with the easy monthly subscription delivery. I completely trust Dr Karam and his products and highly recommend !

  • C
    Carol
    6 days ago
    Rated 5 out of 5 stars
    5 Stars

    Karam MD Trifecta after just using 2 days morning and night, my skin already feels softer, looks brighter and better. I love the product also because it’s easy and is gentle. I just wish it was more affordable for my income.

    CB

  • T
    Terri
    1 week ago
    Rated 5 out of 5 stars
    5 Stars

    I love the Trifecta. My skin has never looked better!

  • ME
    Michael E.
    Verified Buyer
    1 week ago
    Rated 5 out of 5 stars
    Vertical Restore

    Dr. Karam is a perfectionist. He addresses every issue of your facial rejuvenation with exceptional detail and skill. His personality is calming and you immediately know that you are in the presence of someone who is exceptionally competent.

    His staff made me feel like I was their only client . Everyone knew my name and the all participated in my experience . They also all love working for Dr. Karam which says a lot about the practice.

    I am beyond pleased that I selected Dr. Karam and I will enthusiastically recommend him to anyone who is looking to have surgical work done to their face.

    Mike E

    Miami, FL