KaramMD Trifecta

The Complete Anti-Aging Routine

4.7
Rated 4.7 out of 5 stars
1,304 Reviews

A simple skincare system proven to give you healthier, younger-looking skin in 3 easy steps—formulated with powerful active ingredients to target all aspects of aging skin simultaneously.

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MD Formulated

Clinically Proven

Premium Ingredients

For All Skin Types

Cruelty Free

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

Read the KaramMD Journal

Skincare Advice You Can Trust

The Best Anti-Aging Ingredients

The Best Anti-Aging Ingredients

When assessing your skincare products, it is essential they include the following anti-aging ingredients. Each of these ingredients play a unique role in skin health and are crucial to achieving y...

Dr. Karam's Philosophy for an Effective Skincare Routine

Dr. Karam's Philosophy for an Effective Skincare Routine

I believe I’ve finally found the secret to anti-aging. After 20 years of experience—and a lot of patience (and patients) throughout my career—I came to understand that skincare is more than just t...

KaramMD Trifecta skincare routine: Rinse Daily Cleanser, Quench Vitamin C Serum, and Illuminate Anti-Aging Cream held in a single hand.

Trifecta 101: What You Need to Know When Starting Your New Skincare Routine

Whether you’re completely new to skincare or transitioning to the Trifecta system, this guide will walk you through what to expect as you begin your skincare journey.

INGREDIENTS

Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.

*Organic Ingredient

Frequently Asked Questions

Our caring team of experts has the answers.

4.7
Rated 4.7 out of 5 stars
Based on 1,304 reviews
1,304 reviews
  • S
    Sandra
    Yesterday
    Rated 5 out of 5 stars
    Great trio

    This set of skin care products are the best if used so far. It’s gentle to skin but works at the same time. Makes my skin soft, it doesn’t irritate my skin at all. The face wash is so gentle and it takes the make up of easily, I also wash off my mascara with that. I just wish it would be more of the product in the tube.

    I love the vitamin C serum! It’s gentle to my skin, doesn’t irritate or burn the skin. I use before the illuminate cream.

    KS Profile picture for KaramMD Skin
    KaramMD Skin
    35 minutes ago

    Thank you for your wonderful review, Sandra! We're absolutely thrilled to hear about your experience with the Trifecta. It's particularly touching to hear how you've found our formulations to be both gentle and effective—especially how the cleanser works so well at removing makeup while being kind to your skin. These are exactly the kind of thoughtful observations we aim for with our gentle yet powerful formulations. We love that you're experiencing such great results with the Quench Vitamin C serum and how you've discovered the perfect layering technique with the Illuminate cream. Your appreciation of the products' gentle nature while still delivering visible results truly validates our commitment to creating effective, skin-loving solutions. Your trust in our products means the world to us, and we're deeply grateful to have you as part of the KaramMD Skin community. Thank you for sharing your inspiring experience with us!

  • PE
    Pamela E.
    Verified Buyer
    Yesterday
    Rated 5 out of 5 stars
    Very nice so far.

    I’m using all three of these Products + sunscreen for my daytime routine. Love how they simplify and make quick work of what was otherwise taking me to long. They seem to be very high quality products. The ingredients look first class. No fragrance or other objectionable smells. They layer well under makeup. I’ve been using them for three weeks and had no adverse reaction whatsoever. I’m looking forward to great results. In case you wondered why I’m not using the Trifecta twice a day it’s because I’m using Trentinoin, estrogen, and hydroquinone with a peptide moisturizer as my evening routine.

    KS Profile picture for KaramMD Skin
    KaramMD Skin
    34 minutes ago

    Thank you for your wonderful review, Pamela! We're absolutely thrilled to hear about your experience with the Trifecta and how it's streamlined your morning skincare routine. It's particularly touching to hear how you've found our formulations to be both high-quality and efficient—especially how well they layer under makeup while maintaining their effectiveness. These are exactly the kind of thoughtful observations we aim for with our carefully selected, fragrance-free ingredients. We love that you've found a way to incorporate our products seamlessly into your comprehensive skincare journey, complementing your evening prescription treatments. Your appreciation of the products' gentle nature while still delivering results truly validates our commitment to creating effective, skin-loving solutions. Your trust in our products means the world to us, and we're deeply grateful to have you as part of the KaramMD Skin community. Thank you for sharing your inspiring experience with us!

  • ML
    Mimi L.
    Verified Buyer
    Yesterday
    Rated 4 out of 5 stars
    Lovely skincare

    Love the trifecta! Made my skincare routine easy as 1,2,3. Improved my dark spots due to aging. Improved the texture of my skin and softness. I added the Enrich balm. My skin soaks it up! It is not greasy. My wrinkles barely exist!!

    KS Profile picture for KaramMD Skin
    KaramMD Skin
    33 minutes ago

    Thank you for sharing your thoughtful feedback, Mimi ! We're so happy to hear about your positive experience with Trifecta and how it has simplified your skincare routine while delivering such impressive results.

    Your observations about the improvements in dark spots, texture, and softness are exactly what our formula was designed to achieve. It's particularly wonderful to hear that you're seeing such significant improvements in the appearance of your wrinkles - this speaks to the efficacy of our clinically-proven ingredients working together synergistically.

    We're also pleased that you've incorporated Enrich into your routine and are experiencing its fast-absorbing, non-greasy hydration benefits. The combination of Trifecta and Enrich creates a comprehensive approach to supporting your skin's needs, working together to enhance your results.

    The way you've described your routine as "easy as 1,2,3" perfectly aligns with our mission to deliver transformative results through simple, effective skincare. We're honored to be part of your skincare journey and thrilled that you're achieving such wonderful results with our products.

  • PT
    Pamela T.
    Verified Buyer
    2 days ago
    Rated 5 out of 5 stars
    Love love love

    I live in a dry climate and this set along with the barrier balm, keeps my skin hydrated and smooth from flakes

    KS Profile picture for KaramMD Skin
    KaramMD Skin
    17 seconds ago

    Thank you for your wonderful review, Pamela ! We're absolutely thrilled to hear about your experience with the Trifecta and how it's helping you combat the challenges of living in a dry climate. It's particularly touching to hear how you've found our formulations to be so effective at keeping your skin hydrated and flake-free—especially when paired with the Enrich Barrier Balm. These are exactly the kind of results we aim for with our gentle yet powerful formulations. We love that you've found the perfect combination of products to maintain your skin's moisture balance and health, even in challenging environmental conditions. Your enthusiasm and triple "love" truly validates our commitment to creating effective, skin-loving solutions. Your trust in our products means the world to us, and we're deeply grateful to have you as part of the KaramMD Skin community. Thank you for sharing your inspiring experience with us!