KaramMD Trifecta
The Complete Anti-Aging Routine
The KaramMD Trifecta is a simple skincare system proven to give you healthier, younger-looking skin in 3 easy steps—formulated to target all aspects of aging skin simultaneously.
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PRODUCT OVERVIEW
The KaramMD Trifecta is an innovative, clinically proven skincare approach. It consolidates up to 10 product categories into a 3 step routine, making it easy to stay consistent and see results.
Make sure to make sure to use Trifecta consistently twice a day for at least a month to see results. This is critical because it takes 28-days for skin cells to turn over. Significant improvements in texture, tone, and radiance show after 3-6 months.
Skincare doesn’t need to be complicated and the Trifecta offers you a proven path on your journey to great skin.
Size:
- Rinse 2.5 fl oz 75 mL
- Quench 1 fl oz 30 mL.
- Illuminate 1.7 fl oz 50 mL
KEY INGREDIENTS
Aloe Vera: Soothes discomfort and hydrates skin.
Apple Amino Acids: Cleanse without stripping natural oils.
Arnica Extract: Calms irritation and reduces redness.
Broccoli Seed Oil: Supports skin barrier for moisture.
Willowherb Extract: Provides antioxidant protection.
Allantoin: Naturally exfoliates and reduces redness
Triple Vitamin C: Lightens dark spots & boosts natural glow.
Sodium Hyaluronate: Deeply hydrates and plumps skin.
Green Tea: Antioxidant protection and calms irritation.
Willowherb: Balances oil production and calms redness.
Licorice Root: Brightens skin and reduces discoloration.
Panthenol: Stimulates collagen production & skin repair.
Aloe: Hydrates, soothes, and helps reduce skin irritation.
Vitamin E: Strengthens defenses against premature aging.
Encapsulated Retinol: Works deeply to reduce fine lines and wrinkles.
Niacinamide: Balances skin tone and refines texture.
Peptide Complex: Supports the natural repair process.
Lipid Complex: Enhances elasticity and skin barrier.
Sodium Hyaluronate: Boosts hydration to reduce fine lines.
Botanical Lighteners: Naturally reduce pigmentation.
Edelweiss Flower Extract: Firms and protects skin.
Squalene: Strengthens the barrier and locks in moisture.
Hibiscus Flower: Supports body’s natural growth factors
Vitamin C & E: Antioxidants for skin protection and repair.
How to Use
Rinse: Apply to wet skin, massage in circular motions, then rinse clean.
Quench: Apply 2 pumps to slightly damp face, eye area, and neck.
Illuminate: Apply 3 pumps to face, eye area, and neck.
Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.
HOW TO USE: TRIFECTA ROUTINE
How to Use
Rinse: Apply to wet skin, massage in circular motions, then rinse clean.
Quench: Apply 2 pumps to slightly damp face, eye area, and neck.
Illuminate: Apply 3 pumps to face, eye area, and neck.
Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.
HOW TO USE: TRIFECTA ROUTINE
Clinically Proven to Fight Aging Skin
The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:
100% of subjects had improvement in skin’s moisture.
100% of subjects had improvement in fine lines & wrinkles.
91% of subjects had improvement in skin’s firmness.
Clinically Proven to Fight Aging Skin
The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:
100% of subjects had improvement in skin’s moisture.
100% of subjects had improvement in fine lines & wrinkles.
91% of subjects had improvement in skin’s firmness.
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Truly Innovative
Anti-Aging Formulas
1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.
2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.
3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.
Truly Innovative
Anti-Aging Formulas
1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.
2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.
3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.
Great Skin Made Simple
The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta.
Great Skin Made Simple
The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta.
Skincare Advice You Can Trust
The Best Anti-Aging Ingredients
When assessing your skincare products, it is essential they include the following anti-aging ingredients. Each of these ingredients play a unique role in skin health and are crucial to achieving y...
Dr. Karam's Philosophy for an Effective Skincare Routine
I believe I’ve finally found the secret to anti-aging. After 20 years of experience—and a lot of patience (and patients) throughout my career—I came to understand that skincare is more than just t...
Trifecta 101: What You Need to Know When Starting Your New Skincare Routine
Whether you’re completely new to skincare or transitioning to the Trifecta system, this guide will walk you through what to expect as you begin your skincare journey.
INGREDIENTS
RINSE
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
QUENCH
Aqua/Water/Eau, Pentylene Glycol, Magnesium Ascorbyl Phosphate, Aminopropyl Ascorbyl Phosphate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Ziziphus Spina-Christi (Christ’s Thorn) Leaf Extract, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Camellia Sinensis (Tea Camellia) Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Trehalose, Panthenol, Aloe Barbadensis (Aloe Vera) Leaf Juice, Tocopherol, Glycerin, Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Sodium Nitrate, Disodium Phosphate, Polysorbate 60, Citric Acid, Sodium Phosphate, Potassium Sorbate, PPG-26-Buteth-26, Sodium Benzoate, PEG-40 Hydrogenated Castor Oil, Glyoxal, Sodium Metabisulfite, Sodium Hydroxide.
ILLUMINATE
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Caprylic/Capric Triglyceride, Glycerin, Jojoba Oil/Macadamia Seed Oil Esters, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, Coco-Caprylate/Caprate, Dimethicone, Niacinamide, Cetearyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Glucoside, Brassica Oleracea Italica (Broccoli) Seed Oil, Retinol, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Phytosterols, 3-O-Ethyl Ascorbic Acid, Potassium Azeloyl Diglycinate, Leontopodium Alpinum Callus Culture Extract, Squalane, Phytosteryl Macadamiate, Hibiscus Abelmoschus (Musk Okra) Extract, Bellis Perennis (Daisy) Flower Extract, Calendula Officinalis (Marigold) Flower Extract*, Hexylresorcinol, Arnica Montana (Mountain Arnica) Flower Extract, Melissa Officinalis (Lemon Balm) Leaf Extract, Oryza Sativa (Rice) Extract, Leuconostoc Ferment Filtrate, Superoxide Dismutase, Soybean Peroxidase, Tocopherol, Cetyl alcohol, Phenoxyethanol, Biosaccharide Gum-1, Glyceryl Stearate, PEG-100 Stearate, Ceteareth-20, Butylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Polysorbate 60, Sorbitan Isostearate, Xanthan Gum, PEG-20, Sucrose Palmitate, Sucrose Tristearate, Tocopheryl Acetate, Glyceryl Linoleate, Alcohol Denat., Phenethyl Alcohol, Disodium Phosphate, Citric Acid, Potassium Sorbate, Sodium Hydroxide, Iodopropynyl Butylcarbamate, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
Aqua/Water/Eau, Pentylene Glycol, Magnesium Ascorbyl Phosphate, Aminopropyl Ascorbyl Phosphate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Ziziphus Spina-Christi (Christ’s Thorn) Leaf Extract, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Camellia Sinensis (Tea Camellia) Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Trehalose, Panthenol, Aloe Barbadensis (Aloe Vera) Leaf Juice, Tocopherol, Glycerin, Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Sodium Nitrate, Disodium Phosphate, Polysorbate 60, Citric Acid, Sodium Phosphate, Potassium Sorbate, PPG-26-Buteth-26, Sodium Benzoate, PEG-40 Hydrogenated Castor Oil, Glyoxal, Sodium Metabisulfite, Sodium Hydroxide.
Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Caprylic/Capric Triglyceride, Glycerin, Jojoba Oil/Macadamia Seed Oil Esters, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, Coco-Caprylate/Caprate, Dimethicone, Niacinamide, Cetearyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Glucoside, Brassica Oleracea Italica (Broccoli) Seed Oil, Retinol, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Phytosterols, 3-O-Ethyl Ascorbic Acid, Potassium Azeloyl Diglycinate, Leontopodium Alpinum Callus Culture Extract, Squalane, Phytosteryl Macadamiate, Hibiscus Abelmoschus (Musk Okra) Extract, Bellis Perennis (Daisy) Flower Extract, Calendula Officinalis (Marigold) Flower Extract*, Hexylresorcinol, Arnica Montana (Mountain Arnica) Flower Extract, Melissa Officinalis (Lemon Balm) Leaf Extract, Oryza Sativa (Rice) Extract, Leuconostoc Ferment Filtrate, Superoxide Dismutase, Soybean Peroxidase, Tocopherol, Cetyl alcohol, Phenoxyethanol, Biosaccharide Gum-1, Glyceryl Stearate, PEG-100 Stearate, Ceteareth-20, Butylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Polysorbate 60, Sorbitan Isostearate, Xanthan Gum, PEG-20, Sucrose Palmitate, Sucrose Tristearate, Tocopheryl Acetate, Glyceryl Linoleate, Alcohol Denat., Phenethyl Alcohol, Disodium Phosphate, Citric Acid, Potassium Sorbate, Sodium Hydroxide, Iodopropynyl Butylcarbamate, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.
*Organic Ingredient
Frequently Asked Questions
Our caring team of experts has the answers.
How frequently should I be using the Trifecta?
All products should be used twice a day, every day. Adherence to the recommended dosage of twice a day, every day, is paramount. The efficacy of the Trifecta regimen is well-documented in our clinicals, but success hinges on your unwavering dedication. Skipping even a few days can compromise the synergistic effects of the Trifecta regimen, necessitating a reset and extending the timeline to witness desired results.
Do I need different products morning & night?
We believe that cleansing & moisturizing properly are all that is needed to protect your skin from external stressors. The ingredient deck in all three products has been strategically designed to benefit you both am & pm with no need to switch, add or omit products.
How long does the Trifecta last?
The Trifecta should last you around 30 days across all products if using them twice a day as recommended.
Do I need sunscreen with the Trifecta?
Yes! Sunscreen should be part of any daily routine.
When will I see results with the Trifecta?
It takes 28-days for skin cells to turn over, which means in order to see a difference in your skin from KaramMD products, you need to use them consistently for at least a month. That being said, significant improvements, encompassing texture, tone, and overall radiance, manifest with consistent application over an extended period, typically spanning 3 to 6 months. Adherence to the recommended dosage of twice a day, every day, is paramount.
This product is rated 4.7 of 5.0 stars.
It has received 1529 reviews.
- LLisaWhat are your skin concerns? General Aging, Uneven Skin Tone / Discoloration , Environmental Damage, Loss of Elasticity , Fine Lines & Wrinkles2 hours agoWhat are your skin concerns? General Aging, Uneven Skin Tone / Discoloration , Environmental Damage, Loss of Elasticity , Fine Lines & WrinklesRated 2 out of 5 starsExpensive, ? If expired, no noticeable change
I should have stuck with my rule- don’t buy products from surgeons. It’s usually simply a way for them to obtain another income stream . Nonetheless I was excited. The packaging is interesting. But after the first week with no notable skin changes, I consistently noticed the peculiar odor of step 3. It smeells like it’s past its expiration date.
Check out his prices for facelifts. Shameful.I am a retired surgeon .
KSKaramMD Skin26 seconds agoHi, Lisa! Thank you for taking the time to share your feedback. We’re truly sorry to hear that your experience with our products has not met your expectations. At KaramMD, our formulations were developed by Dr. Karam after years of scientific study and formula perfecting, with the goal of creating a simple, effective regimen that delivers meaningful, long-term skin health benefits. Dr.Karam cares deeply about his vision, his products and his customers.
We also wanted to share that visible improvements in skin take time—on average, it takes about 28 days for skin cells to naturally turn over, and often several cycles before lasting changes can be seen. While it’s understandable to want immediate results, consistent use over days, weeks and ultimately months is what leads to the most noticeable improvements.
Regarding your concern about the scent Illuminate, we can assure you that every product is produced in FDA-registered facilities and undergoes rigorous stability and quality testing. The fragrance you’re noticing is a natural byproduct of the active ingredients and not an indication of expiration or spoilage. That said, we take any concerns about product quality very seriously and would be happy to replace your product or investigate further if you’d like to reach out directly to our Customer Care team at customerservice@karammdskin.com
We understand that not every product is the right fit for every individual, and we respect your perspective as both a customer and a retired surgeon. Our goal has always been to provide value and results that go beyond typical skincare, and we are continually learning from the experiences of our customers.
- ALAlejandra L.Verified Buyer19 hours agoRated 5 out of 5 starsBest and fastest customer service
Customer service is the best I have received in a long time, Brittany was very efficient and professional and more than anything they personally take care of you, no recordings and no long calls they immediately respond. Couldn’t have asked for better.
- CGCorina G.What are your skin concerns? General Aging, Loss of Elasticity , Fine Lines & WrinklesYesterdayWhat are your skin concerns? General Aging, Loss of Elasticity , Fine Lines & WrinklesRated 3 out of 5 starsFailed packaging
I love the product, but the Quench packaging is clogging and product is squirting out the pump top. So, I have a half-full bottle of product and no way to use it.
KSKaramMD Skin18 hours agoHi Corina! While we're sorry to hear about the packaging issue with your Quench, we're so glad to see that our Customer Care team was able to step in and make it right with a replacement. Your satisfaction means a lot to us, and we truly appreciate your continued support. If you ever need anything else, we're just a message away!
- GAGena A.Verified BuyerWhat are your skin concerns? General Aging, Fine Lines & WrinklesYesterdayWhat are your skin concerns? General Aging, Fine Lines & WrinklesRated 5 out of 5 starsYUKA App
I'm not sure if Dr. Karam knows this...he probably already does, but the rating for KaramMD quench is poor rating. Moderate risk - Phenoxyethanol.
KSKaramMD Skin23 hours agoWe sincerely appreciate you taking the time to share what you found on the Yuka app, Gena. Phenoxyethanol is a globally approved, broad-spectrum preservative used in skincare and cosmetic products to prevent the growth of harmful bacteria, yeast, and mold. It plays a key role in ensuring product safety. Used at low concentrations (typically ≤1%), phenoxyethanol is considered safe by the FDA, the EU Scientific Committee on Consumer Safety, and other regulatory bodies. It’s a popular alternative to parabens, offering effective preservation without the concerns associated with harsher preservatives like formaldehyde-releasers. While rare, mild irritation can occur in individuals with very sensitive skin, but this is uncommon when used as directed. Phenoxyethanol also helps maintain product consistency over time, making it a critical component in clean, high-performance skincare.
It’s helpful for us to see how our products are being represented, and your message gives us the opportunity to explore this further. Thank you, again!