KaramMD Trifecta

The Complete Anti-Aging Routine

4.7
Rated 4.7 out of 5 stars
1,544 Reviews

The KaramMD Trifecta is a simple skincare system proven to give you healthier, younger-looking skin in 3 easy steps—formulated to target all aspects of aging skin simultaneously.

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Our Packaging Had Some Work Done

✨ A refreshed new look. No scalpel needed.

What has changed?

KaramMD Trifecta now comes with all three products, packaged together as one complete boxed set.


But the products you trust are the same.

Rinse, Quench, and Illuminate's formulas are untouched; the same 3 simple steps you can count on to transform your skin.

Our Packaging Had Some Work Done

✨ A refreshed new look. No scalpel needed.

What has changed?

KaramMD Trifecta now comes with all three products, packaged together as one complete boxed set.


But the products you trust are the same.

Rinse, Quench, and Illuminate's formulas are untouched; the same 3 simple steps you can count on to transform your skin.

MD Formulated

Clinically Proven

Premium Ingredients

For All Skin Types

Cruelty Free

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

Read the KaramMD Journal

Skincare Advice You Can Trust

The Best Anti-Aging Ingredients

The Best Anti-Aging Ingredients

When assessing your skincare products, it is essential they include the following anti-aging ingredients. Each of these ingredients play a unique role in skin health and are crucial to achieving y...

Dr. Karam's Philosophy for an Effective Skincare Routine

Dr. Karam's Philosophy for an Effective Skincare Routine

I believe I’ve finally found the secret to anti-aging. After 20 years of experience—and a lot of patience (and patients) throughout my career—I came to understand that skincare is more than just t...

KaramMD Trifecta skincare routine: Rinse Daily Cleanser, Quench Vitamin C Serum, and Illuminate Anti-Aging Cream held in a single hand.

Trifecta 101: What You Need to Know When Starting Your New Skincare Routine

Whether you’re completely new to skincare or transitioning to the Trifecta system, this guide will walk you through what to expect as you begin your skincare journey.

INGREDIENTS

Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.

*Organic Ingredient

Frequently Asked Questions

Our caring team of experts has the answers.

4.7
Rated 4.7 out of 5 stars
Based on 1,544 reviews
Slide 1 selected
1,544 reviews
  • MR
    Mayra R.
    Verified Buyer
    What are your skin concerns? General Aging, Loss of Elasticity
    19 seconds ago
    What are your skin concerns? General Aging, Loss of Elasticity
    Rated 5 out of 5 stars
    My one & only

    Absolutely convinced best treatment that has touched my skin

    Have convinced a few to try it because they compliment and ask what I use

    Thank you and congrats!!!!

  • SL
    Shauna L.
    Verified Buyer
    What are your skin concerns? General Aging, Fine Lines & Wrinkles, Uneven Skin Tone / Discoloration , Loss of Elasticity , Dryness
    21 hours ago
    What are your skin concerns? General Aging, Fine Lines & Wrinkles, Uneven Skin Tone / Discoloration , Loss of Elasticity , Dryness
    Rated 5 out of 5 stars
    My Peace Treaty With Retinol. No Red, No Peel, All Glow

    I’ve had a long love-hate relationship with retinol products. I love the results, but hate the “why is my face molting?” phase. Trifecta is the first regimen that let me keep the anti-aging power without the redness, peeling, or scary flake-outs. It streamlines what used to be a counter full of jars into one routine that actually plays nice with my retinoid. My skin feels calm, hydrated, and smoother, and I can finally use Retin-A consistently instead of negotiating with it every other night. Bonus: I’m using Trifecta to get my skin healthy and balanced so Dr. Karam has the best canvas possible for a restorative facelift.

    If you’re retinoid-reactive or have sensitive skin but still want serious anti-aging, this is the glow-up without the drama. Consider me impressed and happily volunteering my very available face for future trials.

  • RL
    Roberta L.
    Verified Buyer
    What are your skin concerns? Fine Lines & Wrinkles, Uneven Skin Tone / Discoloration , General Aging, Loss of Elasticity , Skin Texture
    Yesterday
    What are your skin concerns? Fine Lines & Wrinkles, Uneven Skin Tone / Discoloration , General Aging, Loss of Elasticity , Skin Texture
    Rated 2 out of 5 stars
    packaging problem

    I was excited to find a Dr who recommends daily skin care over surgery or other invasive techniques because I really want to believe that the daily products I use are impactful. The cleanser and hydrate portion of this trio work well and have pleasant scents that aren't overpowering. The low star review is for the serum. The serum itself caused everything I put over it (like sunblock or make-up) to go on unevenly and sluff off in patches immediately. After three days of managing this (trying different sunblock and different types of make-up) I decided to only use the serum in the PM. If this had been the end of it I would I would have accepted it and continued to use the products. Unfortunately, a couple of days later, less than one week from receiving and beginning to use the products, the serum nozzle began getting clogged. A several days after that the nozzle was completely clogged, with the nozzle clogged, serum would squeeze out from the pump itself, most of it wasted and now none at all comes out and there seems to be no way to open the container. Bummed I didn't have a solid time frame to see if the product actually works but if I can't get it out of the bottle it doesn't matter either way.

    KS Profile picture for KaramMD Skin
    KaramMD Skin
    1 hour ago

    Thank you so much for your thoughtful review, Roberta! We're so glad to hear you're enjoying the Rinse and Illuminate! Please know our Customer Care team is always here to help with any concerns about product compatibility, layering tips, or packaging. We truly appreciate you and are here for you every step of the way. You can email us at: customerservice@karammdskin.com

  • J
    Janice
    Yesterday
    Rated 5 out of 5 stars
    5 Stars

    I like only 3 bottles

    Easy to use

    Does improve my skin & dark spots

    The office girls are awesome, always helping me

    He has a goid system in place when i need to change dates of delivery & subscription