Better Than Retinol? The Secret Maximizing Your Results

encapsulated retinol

Written by Founder, Amir Karam MD

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For decades, retinol has been hailed as the gold standard in anti-aging skincare, and for good reason.

Decades of research show that it stimulates collagen production, improves fine lines and wrinkles, refines texture, and supports long term skin renewal.

But here is what many people are not told.

Not all retinol works the same way.

If you have ever tried retinol and experienced redness, peeling, or irritation, you were likely using a traditional form. Today, advancements in formulation science have led to encapsulated retinol, also known as slow release retinol, which delivers the same proven benefits with improved tolerability.

So what is the difference between traditional retinol and encapsulated retinol, and which one is better for your skin?

Let’s break it down clearly and simply.

What Is Retinol and How Does It Work for Anti Aging?

Retinol is a vitamin A derivative that converts in the skin to retinoic acid. This active form binds to skin cell receptors and triggers:

  • Increased collagen production
  • Accelerated cell turnover
  • Smoother skin texture
  • Reduction in fine lines and wrinkles
  • Improvement in discoloration and sun damage

It works at a cellular level, which is why it remains one of the most powerful topical anti aging ingredients available without a prescription.

However, the way retinol is delivered into the skin dramatically impacts both results and irritation. Traditional retinol is highly effective, but it has limitations. It absorbs rapidly and releases all at once. That immediate delivery can overwhelm the skin barrier, leading to redness, peeling, dryness, sensitivity, and inflammation.

Additionally, traditional retinol can be unstable. It degrades when exposed to light, air, and heat, which means it doesn't work well for daytime use, and can reduce potency over time if not carefully formulated and stored.

Many people abandon retinol before reaching its long term collagen stimulating benefits simply because the irritation phase feels discouraging.

That is where encapsulated retinol changes the experience.

Encapsulated Retinol vs. Traditional Retinol: What’s the Difference?

Both traditional and encapsulated retinol work to boost cell turnover, smooth skin, boost collagen, and reduce wrinkles. However, encapsulated retinol takes these benefits a step further with enhanced stability, deeper penetration, and improved tolerability.

01. Delivery & Absorption

  • Traditional Retinol: Absorbs quickly and all at once, which means you get a big dose of strong actives in one hit, which can overwhelm the skin.
  • Encapsulated Retinol: Uses controlled, time-released delivery for gradual absorption, ensuring consistent benefits over time, and reduced risk of irritation and

02. Effectiveness & Penetration

  • Traditional Retinol: Works primarily on the skin’s surface, which can cause dryness and irritation, before delivering long-term benefits.
  • Encapsulated Retinol: Penetrates deeper into the skin before activation, targeting the layers where it is most effective while minimizing surface irritation.

03. Stability & Usage

  • Traditional Retinol: Degrades when exposed to air, heat, or sunlight, reducing its potency and making it unsuitable for daytime use.
  • Encapsulated Retinol: Protected by a stabilizing coating, maintaining its efficacy for longer and allowing for both day and night application.

04. Suitability for Different Skin Types

  • Traditional Retinol: Can cause redness, dryness, and peeling, making it challenging for sensitive skin or beginners unaccustomed to actives.
  • Encapsulated Retinol: Designed for better tolerability and suitable for all skin types—including sensitive skin, first-time users, and those incorporating multiple active ingredients into their routine.


Is Encapsulated Retinol as Effective as Traditional Retinol?

Yes. When formulated properly, the time-released, encapsulated retinol delivers the same biological benefits:

  • Collagen stimulation
  • Wrinkle reduction
  • Improved elasticity
  • Smoother texture

But because it is more tolerable, people are more likely to continue using it for the 8 to 12 weeks required to see visible changes.

In clinical practice, I see this often. Patients start traditional retinol, experience irritation, and stop. With slow release retinol, adherence improves dramatically.

And adherence is what drives results.

Why I Chose Encapsulated Retinol for The Trifecta

With its advanced time-release mechanism, improved stability, and reduced irritation, encapsulated retinol is revolutionizing anti-aging skincare—allowing more people to experience its full benefits without the common drawbacks of traditional retinol.

Many give up on retinol too soon due to irritation, never reaching the transformative results it can provide. Encapsulated retinol eliminates this barrier, ensuring that you can consistently incorporate it into your routine without compromising your skin’s health.

By delivering all the advantages of retinol—like increased collagen production, smoother skin, and a youthful glow—without the harsh side effects, encapsulated retinol is a game-changer for long-term skincare success.

The Best Retinol is the One You Can Stick With

The key to seeing real, lasting results is finding a Retinol that works for your skin and sticking with it—because consistency is what truly transforms your skin over time.

That’s exactly why we selected this advanced, time-released retinol as a key ingredient in Illuminate Anti-Aging Cream, the hero product in the KaramMD Trifecta. It delivers all the proven benefits of retinol, without the irritation.

For those who can't use retinol due to pregnancy or aversion to retinoids, Enrich Breathable Barrier Balm offers an alternative solution that doesn’t compromise on results. With Bakuchiol, antioxidants, barrier-strengthening hydration, and comparable anti-aging benefits to retinol, it is the perfect choice for those seeking a gentler approach to skin renewal.

At KaramMD, we believe everyone deserves to feel confident in their skin. With the right ingredients and a results-driven routine, anyone can achieve healthier, stronger, and more rejuvenated skin for years to come.

Amir Karam MD

Board Certified Facial Plastic Surgeon
Founder / Creator of KaramMD Skin

Dr. Amir Karam is a world-renowned facial plastic surgeon specializing in facial and skin rejuvenation. With over two decades of experience, he has helped countless patients achieve a naturally youthful, refreshed appearance. As an innovative surgeon, researcher, textbook author, and speaker, he is a leading authority in his field. Beyond performing surgical procedures that restore a youthful facial shape, he emphasizes the importance of skin quality, ensuring a comprehensive approach to facial rejuvenation. As the founder of KaramMD Skin, he is dedicated to making advanced skincare simple, effective, and accessible—helping you look as young as you feel.

4 comments

MICHELLE GARRETT

I always thought that using tretinoin would give you better results over retinol . Why aren’t you recommending this in your approach to skin care?
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KaramMD Skin replied:
Hi Michelle—Thank you for your comment! Tretinoin wasn’t included here because it requires a prescription but we do have plans to cover it in a future journal article!

Barbara Daros DaRos

Does it tighten up a 72 year old hanging neck ? I wish I had the money to see you. You probably hear this all the time . You sir are a master . I have never in my life seen work like yours . I’ve had 3 different cancers and a hysterectomy which took all my hormones away .Is there any advice to revive my skin ? Will your product help ? Your hands are gold 😊❤️
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KaramMD Skin replied:
Hi Barbara—Thanks for your comment! Your strength and honesty are truly inspiring. To be real, no non-surgical treatment can truly tighten skin laxity, especially in the neck. If they could, surgery wouldn’t be necessary. That said, great skincare can absolutely support your skin’s health, radiance, and texture. We’re here for you if you ever have questions or need guidance. 💛

Karen Henselwood

I have been using prescription Retin-A .1% and compounded Retin-A .1% and Retin-A .05%. My forhead, cheeks and under my eyes look great but my chin has wrinkles. I do not drink out of a straw. I do not expose my skin to the sun at all. I wear about 8 serums during the day with sunscreen. Lasers I have done but still wrinkles on the chin. I do dysport on my chin as well. I am 65. Any other suggestions.
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KaramMD Skin replied:
Hi Karen—Thanks for your comment! It sounds like you’re doing many of the right things. The chin can be a stubborn area, especially as collagen and structural support diminish with age. At 65, volume loss and deeper tissue laxity often play a bigger role than surface treatments can address. You may benefit from targeted collagen-stimulating procedures like RF microneedling or even subtle structural support with fillers or fat transfer, depending on your anatomy. A personalized evaluation would help guide the next best step. Keep up the great work with your regimen!

Suad Picardi

I think Dr Karam is a genius! I love his approach to skincare and plastic surgery when it’s the right time! I’ve always been interested in skincare and would love to pick his brain on Retin A?
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KaramMD Skin replied:
Hi Suad—Thanks for your comment! Retinal (Retin A) is generally considered more potent and faster-acting than retinol, as it requires only one step to convert into retinoic acid, the active form of Vitamin A. While it can be effective, due to its higher potency, retinal may be more likely to cause irritation, redness, or peeling, especially when first introduced to the skin. Retinol, with its slower conversion, is often better tolerated. This is why Dr.Karam chose to use an encapsulated, slow-release Retinol in Illuminate which allows for more consistent use while still delivering results.

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