Trend #1.
Skin Cycling
THE MYTH: Your skin needs frequent breaks from actives to see results, and if it doesn't contain 8-10 steps, it’s ineffective.
Skin cycling is a viral TikTok trend where you rotating active ingredients on a 4-day cycle, instead of using them daily.
The typical schedule looks like: Night 1: Exfoliant. Night 2: Retinoid. Nights 3 and 4: Recovery with moisturizer only. It became popular because it felt structured and “smart.” Rotating actives on a schedule gave people a sense of control, especially if they were already overwhelmed, irritated, or tired of second-guessing. It made skincare feel more organized and manageable, like a clear set of instructions. Put it on a calendar, stick to it, and your skin will behave the way you want it to. But what skin cycling often misses is that this means you use only use a retinoid and exfoliant once or twice a week each. Over a month, that’s only 7 to 8 uses of your retinoid instead of 30 with daily use.
This on and off again cycle is actually not giving your skin it's best chance to acclimate and strengthen over time. Your skin responds best when the input is steady, and the regimen is built around barrier support, stimulating collagen production, and increasing cell turnover.
Consistency over intensity builds tolerance, and tolerance enables progress. If your overall plan keeps changing, it becomes harder to interpret what your skin is reacting to, what it’s benefiting from, and what’s irritating it. For many people, the real lever isn’t “breaks versus actives” – it’s choosing the right active, at the right strength, in a formula that plays well with the rest of your skincare routine.
THE TRUTH: Results come from a steady signal, not frequent breaks.
Actives work best when they support your skin’s natural renewal process in a steady, repeatable rhythm at a strength you can comfortably tolerate. When you take a lot of breaks, you often end up interrupting momentum, making progress feel slower and harder to read.
Instead of using a high-dose retinoid every four days, look for a gentler, well-formulated option, like one that uses Encapsulated Retinol, to help build tolerance, supports cell turnover and collagen support more steadily, and keeps your baseline more stable.
Breaks are sometimes necessary when your skin barrier is irritated, like after a treatment, but they should be a short, strategic response to feedback, not the foundation of your routine.

























4 comments
Janelle
I’ve been using Trifecta for almost a year and I think it is phenomenal! My skin looks bright and people tell me my face ‘glows’. I added Enrich and it is so protective and moisturizing, an added benefit. Now I need to add Polish! This is the best skin care system I have ever used! Thank you for creating it, Dr Karam!
All the best, Janelle
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KaramMD Skin replied:
Hi Janelle—Thanks for your comment! We love hearing that people notice your glow, especially knowing how much care you’ve put into your skin. It’s great that you added Enrich and are feeling that extra layer of comfort and hydration. If you have any questions about incorporating the Polish into your routine, our team is here to assist you. 💖
Sandy Honz
“I have been a loyal user of Trifecta products for nearly four years and am a huge fan of the line. While I have always prioritized high-quality skincare, I especially love the ease of the Trifecta routine and the consistent compliments I receive on my skin. Additionally, I appreciate your helpful updates on treatments like facials, BBL, and Botox—they are incredibly informative!”
Thank you, Sandy Honz
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KaramMD Skin replied:
Hi Sandy—Thanks for your comment! We love hearing that the Trifecta routine has made your skincare so effortless and that you’re seeing consistent results. We’re glad the information we provide has been helpful, too! Your support and trust mean a lot to us. 💛
Linda Tucker
I’ve been a Trifecta fan for about 8 months, my skin color, texture and firmness has never shown this degree of visible changes with any other medical grade products!!!
I am hopeful and anxiously awaiting the release of a body product that will offer the same remarkable improvements as your Trifecta!
A grateful and satisfied customer for life!!!
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KaramMD Skin replied:
Hi Linda—Thanks for your comment! We appreciate you taking the time to write this. It’s exciting to know that your skin has improved so noticeably since using the Trifecta. Your enthusiasm for future products is inspiring, and we’re grateful to have you as part of the KaramMD community. Stay tuned! 😊
Lucille Nicolosi
Dr. Karam, Hello from Jupiter, Florida. I have been using your Trifecta regime products for 5 months now consistently. The ease of use is definitely a dealbreaker for trying anything else. My skin is softer, clearer, and even brighter. The fine lines have diminished…even my neck laxity is more forgiving! Thank you for developing these super products, for educating me with your ongoing articles and newsletters, and your life long commitment to smart skincare. With much gratitude, Lucille N
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KaramMD Skin replied:
Hi Lucille—Thanks for your comment! Dr. Karam’s goal has always been to make skincare both effective and easy to incorporate into a daily routine, and it means a great deal to know that philosophy is resonating with you. We’re grateful for your trust and for being part of the KaramMD community. Keep up the great work! 💞
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