3 Collagen Boosting Skincare Ingredients You Must Have In Your Anti-Aging Skincare Routine

3 collagen boosting skincare ingredients on a background of citrus representing vitamin c
What happens to skin as it ages?

One of the core reasons you begin to see lines, wrinkles, laxity and dull skin is that the production of collagen decreases over time.

Collagen production slows down because of a number of factors, including age, lifestyle, stress, and others. If we don’t stimulate collagen production as we get older, our skin starts to look older, duller, and lined–the skin is on a downward slope. 

Where Does Skincare Fit in When it Comes to Stimulating Collagen Production?

Collagen isn't just a buzzword—it's a crucial component for maintaining youthful, resilient skin.

As we age, collagen levels decline, leading to sagging and fine lines, but skincare products can absolutely turn the collagen “engine” on and rebuild collagen growth over time. The entire reason for putting skincare products on your face is to get your cells to produce collagen again, so if you’re not using a product that gets down to the cellular level to trigger the cells that boost collagen production, you are wasting your time and money.

When I formulated the Trifecta I wanted to develop a product that stimulated collagen for the long run, a product that was easy enough to use every day to reverse collagen loss over time.

Trifecta is a skincare innovation expertly designed to revive your skin's collagen production and combat signs of aging through the consistent use of three simple products, that contain everything you need for healthy, youthful-looking skin.
With its potent blend of carefully selected ingredients, Trifecta penetrates deep into your skin, activating collagen production at the cellular level. Say goodbye to ineffective treatments and hello to Trifecta's transformative power.

So what makes Trifecta so unique and effective? It's the age-defying collagen boosting ingredients that you must have in your skincare routine.

Trifecta's Ingredients That Boast Collagen Boosting in Skincare

There are many things that can help your body boost collagen--the right collagen boosting diet, taking collagen supplements, and effective skincare collagen boosting ingredients. 

Three ingredients that effectively stimulate collagen production at the cellular level include the following:


Retinol, a derivative of vitamin A, plays a pivotal role in skincare due to its remarkable ability to stimulate collagen production and effectively help to counteract the signs of aging, promoting smoother, firmer, and more supple skin.

The inclusion of Retinol in skincare formulations like Trifecta's Illuminate is essential for addressing and preventing the visible signs of aging. By encouraging collagen production, Retinol not only helps to diminish existing wrinkles and fine lines but also works proactively to prevent future signs of aging from developing.

Additionally, Retinol aids in improving skin texture and tone, reducing the appearance of pores, and promoting cellular turnover for a more radiant complexion. Therefore, incorporating Retinol-rich products into your skincare routine can significantly contribute to achieving and maintaining youthful, luminous skin.

Vitamin C

Vitamin C is also instrumental in collagen synthesis. By activating enzymes necessary for collagen formation, Vitamin C contributes to maintaining skin elasticity, firmness, and overall structural integrity.

The inclusion of Vitamin C in skincare formulations like Trifecta's Quench underscores its importance in promoting youthful, healthy skin. By stimulating collagen production, Vitamin C aids in reducing the appearance of fine lines and wrinkles, improving skin texture, and enhancing overall radiance.

Moreover, when combined synergistically with other potent ingredients like retinoids, as seen in the Trifecta line, Vitamin C amplifies the effectiveness of skincare products without causing adverse effects such as inflammation or skin sensitivity.

Therefore, incorporating Vitamin C-rich products into your skincare regimen can help rebuild collagen to nourish, protect, and rejuvenate your skin for a luminous complexion that defies the signs of aging.


Growth Factors

Growth factors are another category of collagen stimulants. Growth factors are essential proteins that regulate cellular processes crucial for maintaining healthy, youthful skin. They play a pivotal role in collagen production, as growth factors signal fibroblasts, the cells responsible for producing collagen, to increase collagen synthesis. This results in improved skin elasticity, firmness, and overall structure, effectively reducing the visible signs of aging. 

In Trifecta, we use Hibiscus flower extract in Illuminate Anti-Aging Cream to support and safeguard the skin's natural growth factors, amplifying their effects on collagen production and skin rejuvenation.

Rich in antioxidants and moisturizing properties, Hibiscus flower extract enhances the skin's resilience against environmental stressors, aiding in the preservation of growth factors and promoting healthier, more youthful-looking skin. 

I explain more about these ingredients and how they work in my video on must-have collagen-boosting ingredients in your skincare routine.

How Do Microneedling or Chemical Peels Contribute to Collagen Production?

Microneedling, laser, chemical peels, or any "prejuvenation" skincare treatment that causes controlled injury to the skin is going to boost collagen. These treatments work, definitely.

But remember, you aren’t going in every day for microneedling or similar treatments. Most people have these more advanced collagen stimulating treatments like chemical peels performed once every three or four months. But, these are not going to be worthwhile if you are not taking care of your skin on a daily basis in between visits.

Using effective skin care every single day actually achieves a gain that is far greater than getting an external treatment every few months. Sustainable skin care that you can do consistently on a daily basis achieves the results you’re looking for much other than any other treatment. 

Watch Out for Factors that Accelerate Collagen Loss

While you’re using the Trifecta, or other skincare routines, on a daily basis, watch out for other factors that negatively impact collagen production.

Be aware of sun exposure and do not smoke. If you’re going to be in out in the sun, protect your skin with a good, broad-spectrum, mineral-based sunscreen.

As you maintain your skincare routine and protect your skin from damage, you will see your skin begin to change. You will see younger-looking, more supple, luminous skin.


Amir Karam MD

Board Certified Facial Plastic Surgeon
Founder / Creator of KaramMD Skin

Dr. Amir Karam is a renowned facial cosmetic surgeon and an authority in his field. With over two decades of experience helping patients achieve a younger, refreshed appearance. In addition to surgical procedures that sculpt a youthfully-defined facial shape, Dr. Karam takes the quality of the skin into account.


Customer Support

Hi Diane—Thank you for your interest in Dr. Karam. Effective skincare products are so important, and Dr. Karam believes the path to great skin is doing the right things consistently over time. That’s why he created the Trifecta, to make effective skincare easy to manage, and we highly recommend using the three prodycts together as a set. The Trifecta bundles all of the most crucial anti-aging components into one clinically proven system, including your Vitamin C serum, and all the other active ingredients you would need like Retinol, Niacinamide, Peptides, Azelaic Acid, etc. which are essential for the longevity of your skin.

By signing up for a Trifecta subscription you’ll automatically receive your products every 30-45 days because if you are using them twice a day as directed, they should last you about that long. Since you are in Canada, you could order more than one set at a time to save on shipping. If you’re interested in setting that up, email us at customerservice@karammdskin.com as we would be happy to create a custom frequency for you to help mitigate some of the extra shipping fees.


Hi there. I am 61 yrs old I do get Botox I have done IPL and now going for micro needling and a peel. To use your product which of course I have fine lines and need to work on my skincare what would I need? How long would it Last? I ask I’m Canadian and with exchange it can become very expensive. I use vitamin c and serum with a neck cream and no7 skin care. Please let me know.

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